Words similar to c-myc

Example sentences for: c-myc

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This compound diminished the hepatic mRNA expression of both c-myc and p53 significantly (Fig 3).
We previously reported that enhanced liver apoptosis in response to the antihepatocarcinogen rotenone was preceded and accompanied by a marked increase in the hepatic levels of c-myc mRNA [ 10 ] , a proto-oncogene that plays a dual role in cell proliferation and apoptosis [ 24 ] . Since in our study [ 10 ] rotenone inhibited hepatocellular proliferation while enhancing apoptosis, we concluded that the increase in c-myc mRNA expression acted as a pro-apoptotic signal in the liver.
Even though Wnt-1 has not been directly implicated in human cancers, many components of the Wnt signaling pathway (such as β-catenin, APC, c-myc, and cyclin D 1) are involved in human tumors including breast cancer [reviewed in ref.
This selection criteria identified c-myc , a gene previously known to have a short-lived mRNA, and an obviously important target of flavopiridol given its role in G1/S phase progression [ 26].
Though c-myc is located on a region that both CGMA and CGH identify as frequently gained, c- myc 's expression is increased more than twofold in less than 6% of the samples.