Example sentences for: c-myc

How can you use “c-myc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Interestingly, mesothelin expression is induced in lung, ovarian, and pancreatic carcinomas where constitutive activation of Wnt signaling is caused by stabilizing mutations in beta-catenin [ 27 28 41 42 43 44 ] . The induction of mesothelin in these carcinomas may be due to misregulation of Wnt signaling as are other targets of the Wnt pathway, c-myc and cyclin D1.

  • Hepatic RNA was extracted and quantified as we reported previously [ 10 ] . RNA was mixed with 32P-labeled c-myc, mdm2, p53, JunB, and β-actin probes, then co-precipitated, purified, and electrophoresed on 5% polyacrylamide gel.

  • Plasmid containing 2.5 kb DNA fragment from c-myc origin region was a kind gift from Michael Leffak, Wright State University Ohio.

  • Increasing amount of ~65 bp long unrelated (non specific) double stranded oligo did not have any effect on this binding activity suggesting that binding of p35 to c-myc origin region is specific.

  • Although its role has remained controversial, it is involved in the increase of immediate early genes such as c-myc [ 63 ] , which is upstream of cyclin D synthesis and necessary for cell division [ 64 ] . In humans, ProTα is coded by a gene family of six members.


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