Words similar to c-myc
Example sentences for: c-myc
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The genes being examined were divided into two groups: I, known TGFβ target genes: pai-1, smad7, c-myc, upa and pthrp (Fig.
For example, the c-myc oncogene has been postulated to drive selection for frequent chromosome 8q amplification.
The effects of PGs on cell proliferation and collagen production have been widely studied in different cell types [ 13 14 15 16 17 26 ] . TXA 2 has been studied extensively because of its apparent role in atherosclerosis, due to its prothrombotic and mitogenic activities on vascular smooth muscle cells [ 15 16 ] . These mitogenic effects are potentiated by growth factors [ 15 16 27 28 ] . In vascular smooth muscle cells TXA 2 stimulates synthesis of bFGF and increases the expression of the proto-oncogenes c-fos , c-myc , and egr-1 , which are associated with entry into the cell growth cycle [ 15 ] . In addition, TXA 2 increases proliferation of fibroblasts [ 13 ] and smooth muscle-like glomerular mesangial cells [ 14 ] .
While mRNA of c-myc was significantly decreased by approximately 25 ± 3% (Fig 3A), that of p53 was also diminished significantly by about 21 ± 5% in the livers of animals treated with RU 486, compared to control mice (Fig 3B).
ARS consensus sequence has been found near the vicinity of c-myc, lamin beta 2 and Dnmt1 replication origin [ 26 ] . Therefore, Identification and characterization of this protein from insect cells and finding its human counterpart will greatly help in elucidating its possible function in DNA replication.
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