Words similar to c-jun

Example sentences for: c-jun

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Results from this study further indicated that PPAR agonists could reduce c-jun activation (Fig.
SMAD4 (DPC4) is essential for this TGFβ 1 signaling and transcriptional activation process [ 16 ] . In epithelial cells, TGFβ 1 decreases c-myc, cdc2 and cyclin D1 expression, and it increases the expression of c-jun and c-fos [ 17 18 19 20 21 22 23 ] . Activation of the TGFβ 1 signal pathway in epithelial cells leads to an increased expression of the cell cycle inhibitors p21 WAF1and p15 Ink4band to a release of formerly sequestered p27 KIP [ 24 25 26 ] . It is assumed that the cooperative action of these cell cycle inhibitors results in the growth arrest mentioned above, although p15 Ink4bdoes not seem to be necessary in this regard.
Of interest to these studies are the three subfamilies within the mitogen-activated protein kinase (MAPK) superfamily including the extracellular signal-related kinases (ERKs), p38 and c-jun N-terminal kinases (JNKs) [ 31 ] . TNFα is one of many cytokines involved in luteal regression.
These results indicated that while 15d-PGJ 2 was very effective in inhibiting c-jun activation, ibuprofen appeared to be ineffective in this regard.
Enhanced expression of c-jun, c-fos, p21 WAF1and p27 KIP, while downregulating PCNA, is dependent on ERK1/2 signaling, an intact cytoskeleton and intracellular calcium (Figures 5, 6A, 7, 8and additional files 6, 7and 8).