Words similar to c-jun
Example sentences for: c-jun
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The JNK pathway is involved in apoptosis [ 13 ] , arginine vasopressin-induced increases in smooth muscle α-actin in vascular smooth muscle cells [ 14 ] as well as in phosphorylation of transcription factors c-jun, ATF-2 and ELK-1 and phosphorylation of Na-K-2CI cotransporter [ 15 ] . The p38 pathway has been implicated in apoptosis [ 16 ] , neointimal hyperplasia after vascular injury [ 17 ] as well as angiotensin ll-induced contraction in vascular smooth muscle [ 18 ] .
PPAR agonists reduced the 25-OH-cholesterol induced c-jun activation and attenuated the cytotoxicity.
These results indicated that while 15d-PGJ 2 was very effective in inhibiting c-jun activation, ibuprofen appeared to be ineffective in this regard.
Results indicated that both cholesterol oxides caused an increase in c-jun in microglia, with 25-OH-cholesterol showing a more pronounced increase (Fig.
Activation of the JNK pathway can lead to the phosphorylation of downstream members including c-jun that belongs to the AP-1 transcription factor family [ 12 52 ] . Because results from this study indicated that JNK pathway was activated by 25-OH-cholesterol, one could expect that AP-1 would be activated in cells treated with cholesterol oxides.