Example sentences for: c-fos

How can you use “c-fos” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Blots were incubated with antibodies to human cyclin H, cdk7, cyclin A, p21 WAF1/Cip1, p27 Kip1, EGFR, activated and total ERK1, c-fos, Fra-1, c-jun, JunB, or β-actin (Santa Cruz Biotechnology) for 16 hours at 4°C.

  • The protein product of this gene is a member of the activating protein-1 (AP-1) family [ 19 ] , which upon binding to either c-fos or fos B protein form a complex that have high affinity to AP-1 binding concensus sequence [ 20 ] . A wide variety of chemicals, including growth factors, and tumor promotors increase the expression of this gene in various cell types [ 21 ] . Compared to untransfected keratinocytes, JunB-transfected cells grew more rapidly, and were highly invasive in an in vitro assay [ 22 ] . Therefore, the increased hepatic levels of junB gene, in mice treated with RU486, was expected to reflect an uncontrolled hepatocellular growth in these animals.

  • Another transcription factor that is involved in regulation of the c-fos SRE is CCAAT/Enhancer binding protein-beta (C/EBPβ).

  • The following antibodies were used in a dilution of 1:1,000: TGFβ 1 (Santa Cruz [sc], sc-146), p-Tyr (sc-7020), β 6 -integrin (sc-6632), α V -integrin (sc-6617), p125 FAK(sc-557), TGFβ 1 -RI (sc-402), TGFβ 1 -RII (sc-400-G), ERK1/2-P (sc-7383), SMAD2/3 (sc-6033), SOS1/2 (sc-259), p130 cas(UBI-06-500), PCNA (sc-56), p21 WAF1(sc-6246), p27 KIP(sc-1641), c-fos (sc-7202), c-jun (sc-44), raf1 (sc-133), p21 Ras(sc-35) and phospho-threonine antibody (New England Biolabs, # 9381).

  • This report demonstrates a new model for c-fos SRE activation in response to Ras-dependent signaling pathways.


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