Words similar to c-fos

Example sentences for: c-fos

How can you use “c-fos” in a sentence? Here are some example sentences to help you improve your vocabulary:

The protein product of this gene is a member of the activating protein-1 (AP-1) family [ 19 ] , which upon binding to either c-fos or fos B protein form a complex that have high affinity to AP-1 binding concensus sequence [ 20 ] . A wide variety of chemicals, including growth factors, and tumor promotors increase the expression of this gene in various cell types [ 21 ] . Compared to untransfected keratinocytes, JunB-transfected cells grew more rapidly, and were highly invasive in an in vitro assay [ 22 ] . Therefore, the increased hepatic levels of junB gene, in mice treated with RU486, was expected to reflect an uncontrolled hepatocellular growth in these animals.
The serum response element (SRE) is located approximately 300 bp upstream of the transcriptional start site in the c-fos promoter and is necessary for serum induction of c-fos [ 2].
These results suggest a cooperative role between the TCF and C/EBPβ transcription factors in regulation of the c-fos SRE in response to Ras-dependent signaling pathways.
Another transcription factor that is involved in regulation of the c-fos SRE is CCAAT/Enhancer binding protein-beta (C/EBPβ).
Since Elk-1 and p35-C/EBPβ synergize in transactivation of SRF-dependent transcription using a GAL4-dependent promoter, we next tested if Elk-1 and p35-C/EBPβ could also synergize in transactivation of a native SRF binding site, namely the c-fos SRE.