Words similar to c-fos
Example sentences for: c-fos
How can you use “c-fos” in a sentence? Here are some example sentences to help you improve your vocabulary:
Since Elk-1 and p35-C/EBPβ synergize in transactivation of SRF-dependent transcription using a GAL4-dependent promoter, we next tested if Elk-1 and p35-C/EBPβ could also synergize in transactivation of a native SRF binding site, namely the c-fos SRE.
In contrast, preincubation with α V - and β 6 -blocking antibodies curbed the TGFβ 1 -induced regulation of p21/WAF1, p27, c-fos, and the p21Ras and ERK1/2 activation, verifying that the binding of TGFβ 1 to the α V β 6 integrin is a prerequisite for the activation of the signal pathway via the α V β 6 integrin.
Induction of Fra-1 and JunB expression was also noted, although the increase was of less magnitude than that observed for c-fos and c-jun.
The protein product of this gene is a member of the activating protein-1 (AP-1) family [ 19 ] , which upon binding to either c-fos or fos B protein form a complex that have high affinity to AP-1 binding concensus sequence [ 20 ] . A wide variety of chemicals, including growth factors, and tumor promotors increase the expression of this gene in various cell types [ 21 ] . Compared to untransfected keratinocytes, JunB-transfected cells grew more rapidly, and were highly invasive in an in vitro assay [ 22 ] . Therefore, the increased hepatic levels of junB gene, in mice treated with RU486, was expected to reflect an uncontrolled hepatocellular growth in these animals.
Portable Network Graphic (PNG) File showing tha regulation of p27, p21, c-fos and c-jun are dependent on α V β 6 integrins, intact cytoskeleton and free intracellular calcium.
Loading...