Example sentences for: c-crk

How can you use “c-crk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Furthermore, we found that the tyrosine phosphorylated Cas SD competed effectively with the endogenous Cas for binding to v-crk and endogenous c-crk, while not affecting tyrosine phosphorylation of proposed upstream proteins such as Fak and endogenous Cas.

  • To determine if the tyrosine-phosphorylated Cas SD chimera affected other signaling pathways, we tested whether the association between c-crk and C3G was affected in NIH3T3 cells expressing the chimera (Fig.

  • 8b, lane 1), while co-expression of the tyrosine phosphorylated Cas substrate domain resulted in reduced association of endogenous c-crk with endogenous Cas and association with the tyrosine phosphorylated chimera (Fig.

  • Immunoprecipitation of endogenous c-crk showed association with endogenous Cas (Fig.

  • Adaptor proteins that regulate tyrosine kinase signaling pathways fall into two major categories, those primarily with protein/protein interaction domains such as SH2, SH3, PTB, and PH domains, exemplified by the adaptor proteins c-crk, nck and grb-2, and those that are primarily tyrosine phosphorylated, exemplified by proteins such as Cas, Dok, IRS-1 and 2, Slp-76, LAT, TRIM or SIT.


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