Example sentences for: c-crk

How can you use “c-crk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As the tyrosine phosphorylated Cas substrate domain acts as a dominant negative for v-crk mediated transformation and JNK activation, and can also interact with v-crk and c-crk (data not shown), we wanted to determine if it could compete for binding of v- and c-crk to endogenous Cas.

  • To determine if the tyrosine-phosphorylated Cas SD chimera affected other signaling pathways, we tested whether the association between c-crk and C3G was affected in NIH3T3 cells expressing the chimera (Fig.

  • Tyrosine phosphorylated Cas SD acts as a decoy for v-crk and endogenous c-crk

  • Furthermore, we found that the tyrosine phosphorylated Cas SD competed effectively with the endogenous Cas for binding to v-crk and endogenous c-crk, while not affecting tyrosine phosphorylation of proposed upstream proteins such as Fak and endogenous Cas.

  • Immunoprecipitation of endogenous c-crk showed association with endogenous Cas (Fig.


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