Example sentences for: btk

How can you use “btk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Btk kinase activity and tyrosine phosphorylation increase upon stimulation of sIgM as well as the IL-5 and IL6 receptors in B cells, and upon crosslinking of the high affinity IgE receptor (FcεRII) in mast cells [ 12, 13, 14, 15].

  • To test whether PLCγ2 is required for Btk:ER-induced calcium mobilization, parental and PLCγ2-deficient cells expressing Btk:ER were treated with 4-HT and/or anti-μ, or ionomycin as a positive control (Fig 4B).

  • 2C), and supports the idea that Btk can perform a kinase-independent adapter function.

  • One possibility is that Btk can directly activate components of the MEKK1/SEK1/JNK signaling cascade.

  • Remarkably, WT Btk:ER induced apoptosis to a similar extent to that seen with BCR cross-linking (Fig 3C), despite the fact that PLCγ2 phosphorylation, calcium mobilization, ERK and JNK were relatively weakly activated (Figs 2, 3A,B).


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