Words similar to btk-deficient

Example sentences for: btk-deficient

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These kinetics are identical to those observed in Btk-deficient cells [ 13].
Kinase activity was not detectable for the K430E mutant of Btk:ER (Fig 1B), comparable to control immunoprecipitations from Btk-deficient cells (data not shown).
In Fig 3A, Btk-deficient cells that express either WT or kinase inactive Btk:ER were treated with 4-HT, or PMA as a positive control, and ERK activity was assessed by immune complex kinase assay using MBP as an exogenous substrate.
However, it should be noted that reconstitution of calcium mobilization in Btk-deficient DT40 cells by kinase inactive Btk was not observed in a previous study [ 11].
As a further control, 4-HT treatment of Btk-deficient cells, expressing Btk without the ER domain, did not induce PLCγ2 phosphorylation (Fig 2B, lanes 9-11).