Words similar to btk-deficient
Example sentences for: btk-deficient
How can you use “btk-deficient” in a sentence? Here are some example sentences to help you improve your vocabulary:
This partially impaired function of Btk:ER in parental cells compared to Btk-deficient cells, in eliciting a biological response, may be due to the presence of endogenous chicken Btk that could compete with Btk:ER for optimal subcellular location.
These kinetics are identical to those observed in Btk-deficient cells [ 13].
However, it should be noted that reconstitution of calcium mobilization in Btk-deficient DT40 cells by kinase inactive Btk was not observed in a previous study [ 11].
In Fig 3C, Btk-deficient cells expressing either WT or kinase inactive Btk:ER were treated with 4-HT and/or anti-μ for 24 hours.
The slow Btk:ER kinetics are consistent with data derived from Btk-deficient cells, in which sustained BCR-induced PLCγ2 phosphorylation, calcium mobilization and MAPK activation are impaired, but the initial responses are relatively normal and appear to be driven by Syk activity (reviewed in reference [ 15]).
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