Words similar to btk-deficient
Example sentences for: btk-deficient
How can you use “btk-deficient” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, it should be noted that reconstitution of calcium mobilization in Btk-deficient DT40 cells by kinase inactive Btk was not observed in a previous study [ 11].
This is in contrast to the Btk-deficient cells analysed earlier (Fig 3), where 4-HT and anti-μ yielded an equivalent apoptotic response.
Btk-deficient cells expressing either WT or kinase inactive Btk:ER were treated with 4-HT or anti-μ and PLCγ2 phosphorylation was analysed by Western blotting (Fig 2A).
The slow Btk:ER kinetics are consistent with data derived from Btk-deficient cells, in which sustained BCR-induced PLCγ2 phosphorylation, calcium mobilization and MAPK activation are impaired, but the initial responses are relatively normal and appear to be driven by Syk activity (reviewed in reference [ 15]).
Kinase activity was not detectable for the K430E mutant of Btk:ER (Fig 1B), comparable to control immunoprecipitations from Btk-deficient cells (data not shown).