Words similar to btk-deficient

Example sentences for: btk-deficient

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This partially impaired function of Btk:ER in parental cells compared to Btk-deficient cells, in eliciting a biological response, may be due to the presence of endogenous chicken Btk that could compete with Btk:ER for optimal subcellular location.
However, it should be noted that reconstitution of calcium mobilization in Btk-deficient DT40 cells by kinase inactive Btk was not observed in a previous study [ 11].
These kinetics are identical to those observed in Btk-deficient cells [ 13].
However Btk:ER was clearly able to induce sustained ERK activity and this, coupled with the findings that in Btk-deficient cells the sustained response is impaired [ 9], suggest that Btk activation may be responsible for the prolonged ERK activation normally detected following BCR cross-linking.
Btk-deficient cells expressing either WT or kinase inactive Btk:ER were treated with 4-HT or anti-μ and PLCγ2 phosphorylation was analysed by Western blotting (Fig 2A).