Words similar to beta-
Example sentences for: beta-
How can you use “beta-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Desensitization occurs both in cell culture systems [ 10 11 12 ] and in the intact animal [ 13 14 ] . In general the mechanisms of desensitization for the alpha-2 adrenergic receptors appear to be similar to those for the beta-2 receptor.
lower) than -35 were pre-selected for a second automatic round of selection: only ligands within 5 A of Ala 135 of the beta-2 subunit and that were hydrogen-bonded to the carbonyl oxygen of beta-2 Ser 133 were retained.
Initial uncoupling of the beta-2 receptor from the G protein after agonist binding is mediated by phosphorylation by G protein-coupled receptor kinase (GRK) of specific residues in the carboxyl tail of the receptor.
There are three subtypes of the alpha-2 adrenergic receptor: alpha-2A; alpha-2B; and alpha-2C [ 15 ] . The human alpha-2A subtype undergoes phosphorylation and short-term desensitization [ 11 12 ] , whereas the human alpha-2C subtype is not phosphorylated [ 16 ] and does not desensitize [ 11 ] . The human alpha-2C subtype, however, does undergo arrestin-dependent internalization [ 17 ] . Many studies [ 11 18 ] , including those from our laboratory [ 10 19 20 ] , have demonstrated agonist-induced down-regulation of alpha-2 receptors, although much less is known about the specific mechanisms for down-regulation as compared to the beta-2 receptor.
The most important of these are the aldose reductase gene ( ALR2 ) [ 17], the insertion/deletion (I/D) polymorphism of the angiotensin I - converting enzyme ( ACE ) gene [ 18, 19], C825T polymorphism of the gene encoding the beta-3 subunit of geterotrimeric G-proteins ( GNB3 ) [ 20, 21, 22], and C677T polymorphism of the methylenetetrahydrofolate reductase gene ( MTHFR ) [ 23].
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