Words similar to beta-adrenergic
Example sentences for: beta-adrenergic
How can you use “beta-adrenergic” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, our finding that a daily injection of the beta-blocker propanolol does not prevent the development of iron deficient cardiac hypertrophy suggests that beta-adrenergic sympathetic stimulation may not be a causal agent in the development of hypertrophy.
Many studies have shown that chronic intravenous infusion of norepinephrine is sufficient to cause hypertrophy, and that various forms of hypertrophy are linked to a decrease in either beta-adrenergic receptor density or a decreased responsiveness to beta-adrenergic stimulation [ 46 48 49 56 57 58 59 60 61 62 63 ] . Barth, for example, showed that norepinephrine infusion induced left ventricular hypertrophy that could be prevented by an adrenergic-receptor blocker [ 58 ] . It has been suggested that ornithine decarboxylase is a link between beta-adrenoreceptors and stimulation of tissue growth factor, which results in hypertrophy [ 64 ] . However, recent studies have focused on alpha-adrenergic reception as a mediator of cardiac hypertrophy [ 35 ] , although some question the role of the alpha-adrenergic receptor as a hypertrophic mediator in vivo [ 34 ] . To date, no published studies of which we are aware have examined alpha-adrenergic reception and the development of cardiac hypertrophy with iron deficiency.
Hence, the beta-adrenergic receptor may be tethered to PKA via gravin.
The failure of the beta-blocker to prevent hypertrophy suggests that, if the sympathetic nervous system is a causal agent in the development of this form of hypertrophy, the signaling mechanism is not mediated by the beta-adrenergic receptor.
Clearly, iron deficient cardiac hypertrophy is not caused by chronic stimulation of beta-adrenergic receptors in the heart.