Words similar to autoantibody
Example sentences for: autoantibody
How can you use “autoantibody” in a sentence? Here are some example sentences to help you improve your vocabulary:
The correlation between PG-specific autoantibody isotype and development of arthritis suggests a pathological role for IgG2a isotype in disease.
For example, testing of nearly 700 sera will be required to determine whether an autoantibody frequency of 5% among CMV seropositive individuals and of 1% among CMV seronegative individuals is a significant difference.
Although direct evidence that autoantigen cleavage fragments produced during cell death elicit autoantibody responses is still scarce, Pollard et al . reported that immunization of B10.S mice (H-2 s) with a 19 kDa proteolytic cleavage fragment of fibrillarin (derived from nonapoptotic cell death) elicited antibodies that are comparable with human anti-fibrillarin autoantibodies and those derived from mice exposed to mercury [ 40 ] . In a study using human sera, Greidinger et al . reported that the recognition of apoptosis-derived and oxidatively modified forms of the 70 kDa subunit of U1 small nuclear ribonucleoprotein autoantigen was associated with distinct disease manifestations [ 41 ] . Furthermore, Oriss et al . demonstrated that a combination of antigen-processing cells and a fragment of DNA topoisomerase I efficiently elicited autoreactive T-cell proliferation, whereas the full-length topoisomerase I required additional stimulus of exogenous interleukin-2 [ 42 ] .
Th1 and Th2 cytokines regulate PG-specific autoantibody IgG isotypes and susceptibility to arthritis.
Apcs deficiency was however associated with markedly increased renal damage, suggesting that this gene may be involved in preventing pathological consequences of autoantibody production.
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