Words similar to autoantibody
Example sentences for: autoantibody
How can you use “autoantibody” in a sentence? Here are some example sentences to help you improve your vocabulary:
We used one-tailed tests to look for an increase in autoantibody as compared to controls and we set P < 0.05 as significant.
Apcs deficiency was however associated with markedly increased renal damage, suggesting that this gene may be involved in preventing pathological consequences of autoantibody production.
Although direct evidence that autoantigen cleavage fragments produced during cell death elicit autoantibody responses is still scarce, Pollard et al . reported that immunization of B10.S mice (H-2 s) with a 19 kDa proteolytic cleavage fragment of fibrillarin (derived from nonapoptotic cell death) elicited antibodies that are comparable with human anti-fibrillarin autoantibodies and those derived from mice exposed to mercury [ 40 ] . In a study using human sera, Greidinger et al . reported that the recognition of apoptosis-derived and oxidatively modified forms of the 70 kDa subunit of U1 small nuclear ribonucleoprotein autoantigen was associated with distinct disease manifestations [ 41 ] . Furthermore, Oriss et al . demonstrated that a combination of antigen-processing cells and a fragment of DNA topoisomerase I efficiently elicited autoreactive T-cell proliferation, whereas the full-length topoisomerase I required additional stimulus of exogenous interleukin-2 [ 42 ] .
The correlation between PG-specific autoantibody isotype and development of arthritis suggests a pathological role for IgG2a isotype in disease.
Role of apoptotic or necrotic fragments in autoantibody production
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