Words similar to autoantibodies
Example sentences for: autoantibodies
How can you use “autoantibodies” in a sentence? Here are some example sentences to help you improve your vocabulary:
Immune dysregulation appears to play a key pathogenic role, as circulating autoantibodies are common in patients with certain JRA clinical subtypes [ 1 2 3 4 5 6 7 ] . Two recent studies have shown a highly significant association between early-onset pauciarticular JRA and circulating antibodies to the 43-kDa nuclear protein DEK [ 8 9 ] . Although circulating DEK antibodies have subsequently been found in children and adults with other autoimmune diseases [ 10 11 ] , these two studies did reveal that children with JRA are significantly more likely to have anti-DEK antibodies than are children without rheumatic disease.
These mice also develop autoimmunity against thyroid and gastric parietal cells [ 22 ] . It is well established that these mice with ovarian autoimmunity also develop circulating autoantibodies against the oocyte cytoplasm, the zona pellucida, and against steroid producing cells [ 22 ] . While we found evidence that one half of our patients had specific antibodies directed against the zona pellucida, we did not find any consistent pattern of immunofluorescence to suggest that our patients had antibodies directed against the oocyte cytoplasm or the steroid producing cells of the ovary.
CMV, a herpes virus, causes chronic asymptomatic infections in immunocompetent individuals, termed latency [ 13 ] . However, in situations of immunocompromise, CMV is reactivated, which in many cases leads to organ failure and death [ 13 ] . Epidemiological reports indicate that chronic CMV infections in humans may play an important role in pathogenesis of vascular diseases such as atherosclerosis [ 14 ] and systemic sclerosis [ 11 12 ] . In addition, a recent report [ 15 ] revealed that SSc autoantibodies bind to CMV late protein UL94 and induce apoptosis in endothelial cells therefore implicating molecular mimicry as a potential mechanism accounting for the link between SSc and CMV.
All patients studied had objective evidence of 1°SS, including keratoconjunctivitis sicca, positive labial salivary gland biopsy, autoantibodies and/or salivary gland hypofunction.
A cohort of patients with synovitis of recent onset was evaluated and we sought to determine the prevalence and potential clinical utility of a spectrum of autoantibodies that has been shown to be associated with RA.
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