Example sentences for: autoantibodies

How can you use “autoantibodies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, while this manuscript was in review, Liu and colleagues reported that anti-peptide autoantibodies and fatal anaphylaxis can be induced in NOD mice that have been immunized with insulin B chain peptides B:9-23 or B:13-23 [ 15 ] . However, in the Liu et al.

  • Sacco and Moghissi detected zona pellucida antibodies in both men and women by indirect immunofluorescence, but they used porcine rather than primate zonae pellicidae [ 27 ] . Normal animal and human serum are known to contain a wide range of low-titer autoantibodies that have been termed "natural autoantibodies" [ 28 ] . Even B cells from newborn mice and human cord blood produce these natural autoantibodies [ 29 30 31 ] . The low titer ovarian antibodies that we demonstrate here in the serum of normal women are likely natural autoantibodies, and not antibodies with any pathophysiologic significance.

  • There continues to be uncertainty as to what stage of the disease each of these autoantibodies develop, and whether they are associated with unique clinical features.

  • TTP-deficient mice exhibit cachexia, with dermatitis, medullary and extramedullary hyperplasia, erosive polyarthritis, and autoimmunity with autoantibodies [ 25 ] . This phenotype is similar to that observed in mice that overexpress TNF [ 26 ] . In agreement with these data, TTP-deficient mice were shown to overproduce TNF, and weekly injections of a neutralizing antibody to TNF eliminated the predominant features of this phenotype.

  • In this study, as illustrated in Table 2, the presence of each of these autoantibodies was significantly associated with having two shared epitope alleles, even when only the RA patients were considered.


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