Example sentences for: autoantibodies

How can you use “autoantibodies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The pathogenic role of IgG2a antibody was also described in a model of autoimmune hemolytic anemia [ 24]; however, these IgG2a autoantibodies were not pathogenic in mice that are deficient in Fcγ receptor III [ 24].

  • These results indicate that CMV infection induces these autoantibodies infrequently and that autoimmune disease associated with CMV infection is probably rare.

  • If CMV was a frequent inducer of autoantibodies, and by implication an autoimmune disease, both the frequency of autoantibodies in disease-free individuals and the incidence of autoimmune disease in the general population would be much higher than observed by other workers and ourselves.

  • In the present study, we show that anti-peptide autoantibodies and fatal anaphylactic reactions can be elicited by immunodominant GAD65 peptides in NOD mice that have been injected with these peptides intraperitoneally in incomplete Freund's adjuvant (IFA), as part of an attempt to induce "tolerance" and prevent the spontaneous development of T1DM.

  • Casciola-Rosen and coworkers have proposed that modifications of autoantigens during cell death, particularly proteolytic cleavage, might be crucial for the generation of autoantibodies in autoimmune diseases [ 23 37 ] . Unique proteolytic fragments of α-fodrin and type 3 muscarinic acetylcholine receptor have been implicated in the generation of autoantibody responses in primary Sjögren's syndrome [ 38 39 ] .


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