Example sentences for: angiopoietin

How can you use “angiopoietin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Various growth factors such as angiopoietin (ang)-1, platelet-derived growth factor, transforming growth factor-β as well as VEGF-A are also involved in arteriogenesis, and it may therefore be necessary to use combinations of these factors to obtain stable and mature vessels (Fig.

  • ang = angiopoietin; CEP = circulating endothelial precursor; FGF = fibroblast growth factor; FGF-1 = acidic fibroblast growth factor; FGF-2 = basic fibroblast growth factor; HIF-1α = hypoxia inducible factor-1 alpha; SPECT = single photon emission computed tomography; VEGF = vascular endothelial growth factor.

  • Angiopoietin related protein (AngRP) (Fig.

  • Tie1 is an orphan receptor, whereas the ligands of Tie2 receptor have been identified as angiopoietin (Ang)-1 and Ang-2 [ 5 6 ] . Ang-1 has been shown to be responsible for recruiting and sustaining periendothelial support cells [ 7 ] . It has been reported that Ang-2 disrupts blood vessel formation in the developing embryo by antagonizing Ang-1-induced autophosphorylation of Tie2 [ 6 ] . Transgenic mouse models of Tie2/Ang-1 result in embryonic lethality due to absence of remodeling and sprouting of blood vessels [ 7 8 ] . The physiologic roles of the Tie2 receptor and its ligands are limited to angiogenic processes that occur subsequently to the earlier vasculogenic and angiogenic actions of vascular endothelial growth factor (VEGF) and its receptors [ 7 ] . VEGF and the Tie family orchestrate optimal blood vessel formation [ 9 10 ] .

  • Ang = angiopoietin; BSA = bovine serum albumin; FBS = fetal bovine serum; HMVEC = human microvascular endothelial cell; OA= osteoarthritis; PCR = polymerase chain reaction; RA = rheumatoid arthritis; RT-PCR = reverse transcription polymerase chain reaction, SE = standard error; Tie = receptor tyrosine kinase; VEGF = vascular endothelial growth factor.

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