Example sentences for: angiogenesis

How can you use “angiogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, the identification and dissection of the cellular and molecular pathways associated with EC activation may reveal novel clues which could provide further understanding of biological processes such as wound healing, vascular permeability, and angiogenesis among others.

  • SLC/CCL21 is documented to have direct anti-angiogenic effects [ 28 29 ] ; the tumor reductions observed in this model could have been due to participation by T cells secreting IFNγ leading to inhibition of angiogenesis via MIG/CXCL9 and IP-10/CXCL10, as well as T cell-dependent immunity [ 16 ] . IFNγ mediates a range of biological effects that facilitate anticancer immunity.

  • VEGF-A is the prototypic member of a family of secreted, homodimeric glycoproteins with endothelial cell-specific mitogenic activity and the ability to stimulate angiogenesis in vivo [ 2].

  • EC activation is a program of gene-expression that could affect angiogenesis, permeability, and inflammation that are closely associated with a large number of vascular diseases.

  • It is well established that, besides the MHCII molecules, IFNg can induce susceptible tumors to upregulate the expression of MHC class I antigens [ 43 ] , tumor associated antigens [ 44 ] , costimulatory molecules [ 45 ] , and heat shock proteins [ 46 ] . In addition, IFNg may have antimetabolic and antiproliferative influence on certain types of tumor cells [ 47 ] . It has also been suggested that IFNg may cause responding tumor cells to secrete angiogenesis inhibitors [ 48 ] . As it is not known which of those IFNg effects are missing or restored by PMA in LS1034 cells, a thorough evaluation of the possible clinical implications of our in vitro findings is quite difficult.


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