Example sentences for: androgen-mediated

How can you use “androgen-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Future studies aimed at eliminating CSN5 activity will show whether it is involved in androgen-mediated p27 control.

  • Here, we used the androgen-sensitive human prostate cancer cell line LNCaP [ 39 ] as a model system to address the role of SKP2 in androgen-mediated cell cycle control.

  • Finally, consistent with SKP2 and p27 being integral components of androgen-mediated growth control of LNCaP cells, CA also efficiently reversed the MIB-induced G1 cell cycle arrest (Fig.

  • Our data suggest that androgen-mediated SKP2 downregulation is responsible for decreased ubiquitylation and accumulation of p27 in LNCaP cells, an effect that is readily overcome by overexpression of SKP2.

  • SKP2 overexpression is sufficient to overcome androgen-mediated p27 accumulation, indicating that it is a major mediator of androgen-mediated cell cycle control.


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