Words similar to androgen-responsive
Example sentences for: androgen-responsive
How can you use “androgen-responsive” in a sentence? Here are some example sentences to help you improve your vocabulary:
Structurally different androgens elicit different patterns of response from several androgen-responsive promoters, suggesting that the type of ligand present could affect cellular response [ 17 ] . Mitogen-activated protein kinase 14, and STAT-induced STAT inhibitors 2 and 3 were expressed at significantly higher levels in cells with wild-type AR.
Responses to androgen of the set of transcripts identified as androgen-responsive in the LNCaP experiments were examined in each of these cell lines.
We were curious to know whether the expression changes observed in LNCaP would also occur in other androgen-responsive human prostate cancer cell lines (MDA PCa 2a, MDA PCa 2b, and LAPC-4), or in LNCaP and LAPC-4 subclones carried in androgen-depleted conditions for extended periods.
Stat3 has been shown to enhance AR-mediated PSA expression and AR transcriptional activity in prostate cancer cells [ 16 25 28 ] . We used two well-characterized androgen-responsive luciferase reporter plasmids to study the effect of Stat3 on AR-mediated transcriptional activity.
Additional experiments using physiological concentrations of androgen (for example, 0.01 - 1 nM methyltrienolone) also failed to disclose any androgen-responsive genes (data not shown).