Example sentences for: androgen-responsive

How can you use “androgen-responsive” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Structurally different androgens elicit different patterns of response from several androgen-responsive promoters, suggesting that the type of ligand present could affect cellular response [ 17 ] . Mitogen-activated protein kinase 14, and STAT-induced STAT inhibitors 2 and 3 were expressed at significantly higher levels in cells with wild-type AR.

  • Responses to androgen of the set of transcripts identified as androgen-responsive in the LNCaP experiments were examined in each of these cell lines.

  • We were curious to know whether the expression changes observed in LNCaP would also occur in other androgen-responsive human prostate cancer cell lines (MDA PCa 2a, MDA PCa 2b, and LAPC-4), or in LNCaP and LAPC-4 subclones carried in androgen-depleted conditions for extended periods.

  • Stat3 has been shown to enhance AR-mediated PSA expression and AR transcriptional activity in prostate cancer cells [ 16 25 28 ] . We used two well-characterized androgen-responsive luciferase reporter plasmids to study the effect of Stat3 on AR-mediated transcriptional activity.

  • Additional experiments using physiological concentrations of androgen (for example, 0.01 - 1 nM methyltrienolone) also failed to disclose any androgen-responsive genes (data not shown).


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