Example sentences for: androgen-responsive

How can you use “androgen-responsive” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • et al . found significantly different baseline expression levels of insulin-like growth factor (IGF) and insulin-like growth factor binding protein (IGFBP) between normal and AIS-derived genital skin fibroblasts, and could not detect changes in transcript levels in response to androgen treatment [ 29 ] . In normal genital fibroblasts, androgen-responsive reporter genes can only be activated by expression of co-transfected AR in the presence of ligand [ 30 ] . Therefore, endogenous AR expression itself may be insufficient in genital skin fibroblasts to elicit a transcriptional response.

  • Additional experiments using physiological concentrations of androgen (for example, 0.01 - 1 nM methyltrienolone) also failed to disclose any androgen-responsive genes (data not shown).

  • An additional set consists of 30 androgen-responsive genes with roles in protein trafficking and secretory vesicle formation and in transport of secretory vesicles (Figure 5a).

  • , unpublished observations) and over 200 of these are among the androgen-responsive genes (see [ 12] and Additional data files).

  • Responses to androgen of the set of transcripts identified as androgen-responsive in the LNCaP experiments were examined in each of these cell lines.


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