Example sentences for: androgen-induced

How can you use “androgen-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Such a mediator could be AS3, a gene induced by growth inhibiting levels of androgen with kinetics that precede cell cycle arrest [ 52 ] . In addition, AS3 overexpression mimics androgen-mediated cell cycle arrest in MCF7 cells stably expressing exogenous AR, while anti-sense AS3 confers resistance to androgen-induced growth arrest [ 53 ] . The function of AS3 is still unknown, but the encoded protein has features of a potential transcription factor [ 53 ] .

  • Whether it functions in the processing of androgen-induced secretory proteins or in other pathways induced by androgens or perhaps even in cell-cell signaling is unclear, but the degree of induction suggests it may have an important role in prostatic physiology.

  • Further investigation into androgen-induced changes in gene and protein expression in vitro and in vivo will undoubtedly shed light on prostatic physiology and prostatic carcinoma, and also on broader physiological functions of androgen.

  • Yet other pathways may not be direct targets of AR activation but could be modulated in response to androgen-induced changes in the internal or external milieu of the cells.

  • Unlike in rat fibroblasts and human U87 cells [ 29 30 32 ] , SKP2 overexpression is not sufficient to override androgen-induced G1 arrest in LNCaP cells, despite a profound effect on p27 levels (Fig.

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