Words similar to aminoacyl-t
Example sentences for: aminoacyl-t
How can you use “aminoacyl-t” in a sentence? Here are some example sentences to help you improve your vocabulary:
Translational elongation factor-1 interacts with guanine nucleotides, 80S ribosomes, and aminoacyl-tRNAs.
The sequence identity within the HisRS domain of IfkA/B and yeast GCN2 is 28%, with strong conservation within the M1, M2, and M3 motifs that are characteristic of class II aminoacyl-tRNA synthetases [ 37 ] . The similarity between the kinase domains is much higher, with IfkA/B possessing 44% identity with yeast GCN2, with high conservation of all of the kinase subdomains.
Aminoacyl-tRNA synthetases catalyze a succession of reactions, which involve: hydrolysis of the α-β phosphate bond in ATP; condensation of AMP with the cognate amino acid, resulting in the formation of an aminoacyl-adenylate; displacement of the AMP moiety of the aminoacyl-adenylate with the cognate tRNA, producing aminoacyl-tRNA.
Hence, considerable diversity of protein domains appears to have emerged prior to the "crystallization" [ 95 ] of a transcription machinery similar to the one that operates in modern cells and probably had been already in place in LUCA [ 96 ] . Similar conclusions regarding the early stages of protein domain evolution have been reached previously as a result of evolutionary analysis of proteins involved in translation, such as aminoacyl-tRNA synthetases and GTPases: substantial diversification of protein domains had occurred prior to the "crystallization" of elaborate, modern-type translation machinery [ 66 97 ] .
The Zn-ribbons are widespread, small domains that are comprised of two β-hairpins bounded by consecutive extended regions stabilized by metal-coordinating residues in the hairpin loops [ 67 68 69 70 ] . Zn-ribbons are present in a variety of nucleic-acid-binding proteins, including several ribosomal proteins, translation factors, aminoacyl-tRNA synthetases, RNA polymerase cofactors in archaea and eukaryotes, and several transcription factors.
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