Words similar to alphaa
Example sentences for: alphaa
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In five week old alphaA/BKO lenses, Sytox green stained nuclei (green) in the anterior epithelium, equatorial/bow, and posterior subcapsular regions (Figure 2A).
In 5 wk alphaA/BKO lenses there was a high density of stained membranes per unit area throughout the cortex, with no nucleic acid staining in these regions.
Alpha-Crystallin is comprised of two polypeptides, alphaA-crystallin (alphaA) and alphaB-crystallin (alphaB), which share 55% amino acid sequence homology [ 1 ] . They are the most abundant proteins in lens fiber cells [ 2 3 ] and exist as heteroaggregates of approximately 800 kDa that can undergo inter-aggregate subunit exchange [ 4 ] . The expression of these two proteins in the lens epithelium, however, is not uniform throughout different regions of the anterior epithelium.
Although this property may be a major contributor to the maintenance of lens clarity, the early changes in the alphaA/BKO lenses indicate a much broader cellular function for alpha-crystallin.
In 5 and 54 wk old alphaA/BKO lenses, superficial and deep anterior cortical regions, stained for lipid membranes, did not reveal any patterns typical of fiber cells cut in cross-section or longitudinal section.
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