Example sentences for: alphab

How can you use “alphab” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several heat shock proteins have been found in cell nuclei in the absence of stress [ 30 ] , and alpha-crystallin has been shown to interact directly with DNA [ 18 ] . AlphaB, expressed in transfected CHO cells, has been shown to ectopically localize to interphase nuclei, suggesting a regulatory role for this protein in the nucleus [ 19 ] . A subset of immortalized lens epithelial cells from alphaBKO mice have been shown to hyperproliferate [ 20 ] suggesting that alphaB may be important in maintaining genomic stability.

  • In the single alpha-crystallin knockout mice, the remaining alpha-crystallin may fully or partially compensate for some of the functions of the missing protein, especially in the lens, where both alphaA and alphaB are normally expressed at high levels.

  • Both alphaA and alphaB can bind specifically to actin, both in vitro [ 13 ] and in vivo [ 14 ] . Actin filament formation has been shown to be necessary for the differentiation of lens epithelial cells [ 15 ] , however, the significance of alpha-crystallin interaction with actin in differentiation is not known.

  • This process did not appear to have proceeded normally in lenses lacking alphaA and alphaB.


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