Example sentences for: alpha-crystallin

How can you use “alpha-crystallin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Both alphaA and alphaB can bind specifically to actin, both in vitro [ 13 ] and in vivo [ 14 ] . Actin filament formation has been shown to be necessary for the differentiation of lens epithelial cells [ 15 ] , however, the significance of alpha-crystallin interaction with actin in differentiation is not known.

  • In the current study, the observation of a disorganized pattern of nuclei localized to the equatorial bow region of alphaA/BKO lenses, and nucleic acid staining of structures throughout the anterior cortex of 54 wk alphaA/BKO lenses, is consistent with a role for alpha-crystallin in the nucleus.

  • The results indicate that alpha-crystallin is necessary for proper fiber cell formation and resulting lens transparency.

  • All of these findings raise many questions as to the possible role(s) of alpha-crystallin in the nucleus and in cell cycle regulation during differentiation.

  • One approach to resolving some of the in vivo functions of alpha-crystallin is to generate animal models where one or both of the alpha-crystallin gene products have been eliminated.


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