Words similar to alpha-
Example sentences for: alpha-
How can you use “alpha-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Moreover, macrophages actually had a lower content of alpha-tocopheryl quinone when incubated with alpha-tocopherol alone then when incubated with both alpha- and gamma-tocopherol together.
Both alpha- and gamma-tocopherol are absorbed from the intestine and secreted into chylomicrons equally well [ 6 7 ] . The selective retention of alpha-tocopherol in plasma is attributed to a number of factors such as the hepatic alpha-tocopherol transfer protein (alpha-TTP), which preferentially incorporates alpha-tocopherol (over gamma-tocopherol) into very low density lipoprotein [ 8 9 10 ] . Indeed, the affinity of the different forms of vitamin E for the alpha-TTP protein appears to be a primary determinant of their plasma levels [ 8 ] . In addition, there is evidence suggesting that gamma-tocopherol is preferentially catabolized to a water-soluble form (2,7, 8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman or gamma-CEHC) by side chain oxidation [ 11 12 ] .
Several lines of evidence suggest that elevated catecholamine levels are cardiotoxic [ 15 ] . Elevated plasma norepinephrine levels are hypothesized to cause direct myocardial damage through many mechanisms, which may be amplified by concomitant alpha-1 blockade.
Peripheral alpha-1 antagonists also cause neurohormonal changes during chronic therapy.
In the sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI), peripheral alpha-1 antagonists are recommended not only as second-line anti-hypertensive therapy after low-dose diuretics and beta blockers, but also for specific indications such as therapy in men with hypertension and prostatism [ 2 ] . Alpha-1 antagonists represent effective therapy for prostatism, and fifty percent of men have histologic evidence of BPH by 60 years of age [ 3 4 ] . The National Ambulatory Medical Care Survey reported that the number of people on any type of peripheral alpha-1 antagonist in 1995 was approximately 6 to 7% of those with hypertension [ 5 ] . About 80% of surveyed physicians would choose these drugs as a first-line blood pressure agent for patients with hypertension and symptoms of BPH [ 6 ] .
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