Example sentences for: alpha-

How can you use “alpha-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The human alpha-2C receptor is somewhat unique among the alpha-2 receptors in that it does not appear to undergo agonist-induced down-regulation [ 11 ] . The human alpha-2A adrenergic receptor, which does undergo down-regulation, has an acidic serine motif (EESSSSD) in the third intracellular loop.

  • In contrast, norepinephrine is more potent at down-regulating the alpha-2B and alpha-2C subtypes, with a concentration of only 70 nM required to produce half-maximal down-regulation.

  • In rats, norepinephrine stimulates apoptosis, which is mediated through beta receptors [ 16 ] . In addition, alpha-1 cardiac receptors inhibit this response in rat myocytes [ 17 ] . The increased concentration of norepinephrine leading to cardiac beta receptor stimulation combined with alpha-1 receptor inhibition may lead to increased apoptosis in myocytes.

  • The human alpha-2C receptor, by contrast, has a DESSAAAE sequence in the same region [Figure 2; [ 22 ] ]. Thus, it is possible that the lack of desensitization and perhaps also down-regulation of the human alpha-2C receptor is due to the fact that there are only two hydroxyl residues in the DESSAAAE motif rather than the four hydroxyl residues in the alpha-2A EESSSSD motif.

  • [ 14 ] found a similar incorporation of both alpha- and gamma-tocopherol into RAW264.


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