Words similar to allelic
Example sentences for: allelic
How can you use “allelic” in a sentence? Here are some example sentences to help you improve your vocabulary:
These tumors had previously been shown to have undergone allelic deletion on chromosomes 3p (77%), 9p (75%), 11p (37%), 13q (39%), 16q (85%), 17p (100%) and 17q (71%).
[ 4 ] , this showed equal allelic representation in cDNAs from various fetal and adult tissues, and a strong maternal bias in the placenta (Fig.
Likewise, Arabidopsis PAI2 and PAI3 genes that have been trans-methylated by the PAI1/PAI4 locus do not transfer their methylation status to naive singlet genes [ 12 ] . In fact, there are few well-documented cases for the non-allelic relay of trans-silencing ability [ 11 24 ] . Does this amount to an operational difference between allelic (paramutation) and non-allelic (trans-silencing) interactions, or does it simply reflect a lack of data?
One of the two known genes for which allelic variation was identified within its coding region sequence was Slc5a7 . This encodes a high-affinity choline transporter expressed in the brain and spinal cord and may be considered a plausible candidate gene for underlying the QTL (see Discussion).
M6P/IGF2R allelic loss would therefore result in enhanced cellular bioavailability of this potent growth factor, thereby potentially increasing both cell proliferation and resistance to apoptosis [ 29 ] . The M6P/IGF2R also facilitates the activation of TGFβ, a potent cell growth inhibitor that is secreted in an inactive form (reviewed in [ 15 16 ] ). M6P/IGF2R mutation is therefore one mechanism by which cancer cells can become refractory to TGFβ's mitoinhibitory effect.
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