Words similar to allelic
Example sentences for: allelic
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Several groups of Arabidopsis mutants that are resistant to the inhibitory effects of high sugar concentrations have been isolated [ 46 47 48 49 50 ] . Characterization of these mutants reveals that the sis5 [ 46 ] , sun6 [ 50 ] , gin6 [ 49 ] and isi3 [ 45 ] mutants are allelic to the abscisic acid insensitive mutant abi4 [ 51 ] and the sis4 [ 46 ] , isi4 [ 45 ] and gin1 [ 45 ] mutants are allelic to the abscisic acid biosynthesis mutant aba2 [ 52 ] . In addition, the ethylene constitutive response mutant ctr1-1 [ 53 ] , as well as the ethylene-overproduction mutant eto1 [ 54 ] , display sugar-resistant phenotypes [ 48 ] . Conversely, the sugar-response mutant sis1 exhibits an ethylene constitutive response phenotype and is allelic to ctr1-1 [ 47 ] . The prl1 mutant, which exhibits increased sensitivity to exogenous sugars [ 55 56 ] , carries a mutation in a gene that encodes a WD protein that interacts with SNF1 protein kinases [ 57 ] .
We show that, once several factors were addressed, such as sequencing error detection and discrimination between closely related genes, a high-throughput pipeline could be developed that allows large numbers of gene-coding regions from QTL intervals to be rapidly compared in silico and interstrain allelic sequence differences quickly identified and targeted for further hypothesis-driven analyses.
Entire lobules and large ducts of normal breast tissue can be derived from a single progenitor cell [ 47 ] , and LOH at various chromosomal locations is frequently detectable in morphologically normal lobules adjacent to breast tumors [ 48 ] . Lung tumors and head and neck tumors that develop in a localized region also often have a common clonal origin [ 3 4 49 ] . The high frequency of M6P/IGF2R loss of heterozygosity observed in the head and neck tumors in this study suggests that the phenomenon of "field cancerization", first described by Slaughter and his colleagues [ 2 ] in 1953, may in part result from the clonal proliferation of mucosal epithelial cells with M6P/IGF2R allelic loss.
As mentioned above, VNTR Locus-4 of the B. suis biovar 1 sequenced genome was 11-bp larger than the homologous regions of B. abortus biovar 1 and B. melitensis biovar 1. When the sizes of the VNTR Locus-4 fragments amplified from the panel of Brucella strains were compared to the size range of the normal and the alternative alleles, we observed that the products amplified from B. canis , B. neotomae , B. ovis , and B. suis biovars 2, 4 and 5, were consistent with the 11-bp offset allelic ladder of B. suis biovar 1 rather than the allelic ladder exhibited by the B. melitensis or B. abortus biovars (Fig.
The filtered BLAST results from the B6 and D2 strains were then aligned using AutoAssembler and allelic sequence variations were detected.
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