Example sentences for: allele

How can you use “allele” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, direct estimates of the allele-specific effects of heterozygosity (relative to the corresponding homozygotes), nearly absent in the infectious disease-HLA literature, are frequently found in studies of HLA genotype and chronic (mostly autoimmune) diseases [ 28 29 30 ] . We do not know the reason for this difference in approach, but suspect that some infectious disease investigators, informed by the evolutionary hypothesis of overdominance for infectious disease resistance and by animal studies, may have a special interest in detecting effects of heterozygosity per se . Many studies of HLA-autoimmune disease associations, on the other hand, seem to focus more on the effects of individual alleles and, having established these, move on to investigate the dependence of these effects on genetic modifiers, including the identity of the individual's other allele at the same locus.

  • The albino mice were homozygous and coisogenic for a mutant allele of tyrosinase ( Tyr c -2 J ) that arose on the otherwise pigmented B6 background.

  • Analysis of allele discrimination during the OCP ligation step of the assay

  • This odds ratio provides an approximation of the relative risk that is associated with the non-functional allele B 2 by virtue of its association with the disease allele A 2 .

  • Our original hypothesis was that the allele, which is associated with increased BMD, was also associated with higher insulin levels and insulin resistance.


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