Example sentences for: alleles

How can you use “alleles” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Simple and accurate methods exist to determine for a single pair of alleles how the three possible genotypes (2 homozygotes and one heterozygote) affect disease outcome, and these methods have been used frequently in the literature on autoimmunity and HLA [ 28 29 30 ] and once (to our knowledge) in the HLA-infectious disease literature [ 33 ] . It is of additional interest for epidemiologists, immunologists, vaccine designers and evaluators, and population geneticists to know whether HLA heterozygosity in general improves the immune response to and outcome of infectious diseases.

  • Example 2: Suppose there are 10 alleles, each with frequency 5%, each conferring resistance to a particular disease, and one allele, with frequency 50%, conferring susceptibility.

  • In fact, real alleles will likely have a spectrum of effects, ranging from highly resistant, to highly susceptible, with some alleles having "no effect."

  • For the present analysis, all haplotypes were defined only by A and B alleles, and the ancestral haplotype was defined as a hemochromatosis-associated Ch6p bearing A*03-B*07 and HFE C282Y.

  • STRPs alleles are usually identified and labelled as the length of the PCR product as measured on denaturing polyacrylamide gels.


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