Example sentences for: allele-specific

How can you use “allele-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • P1 is an "Amplifluor™"-primer, with a 5' hairpin and loop structure with a fluorophore and quencher at the base of the hairpin arms [ 13 12 16 ] . The two allele-specific OCPs have different backbone sequences complementary either to a FAM- or TET- labeled P1 allowing discrimination of the polymorphic base.

  • Two examples are given to illustrate the reasons for the lack of concordance between population and allele-specific effects.

  • Our results do not deny that allele-specific overdominance at HLA exists in human populations with respect to infectious disease resistance, but simply raise doubts about the reliability of the major evidence that has been adduced in support of this phenomenon.

  • As a control for these assays, we assessed the allele-specific expression of the Obph1 gene, using the same cDNA preparations.

  • Having established that DEK and NF-Y in nuclear extracts participate in the HLA-DQA1*0101 binding complex, we used recombinant full-length DEK (rDEK) to determine whether it alone can bind to Y-box motifs and to examine how gene- and allele-specific sequence polymorphisms alter its binding.


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