Words similar to allele-specific

Example sentences for: allele-specific

How can you use “allele-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

P1 is an "Amplifluor™"-primer, with a 5' hairpin and loop structure with a fluorophore and quencher at the base of the hairpin arms [ 13 12 16 ] . The two allele-specific OCPs have different backbone sequences complementary either to a FAM- or TET- labeled P1 allowing discrimination of the polymorphic base.
Illustrating that allele-specific cis -acting sequences must dictate TAS-position use, alleles differ at most TAS positions: only 3 are used by all alleles; 24 positions (†-marked) are used by more than one, but not all alleles, and 19 positions (*-marked) are used by only one allele.
The backbone-specific 5' region of the allele-specific P2s not only increases the Tm of the primer to that desired for the assay, but also confers OCP specificity.
In this report, we show that although population heterozygote advantage is compatible with allele-specific overdominance, it is also compatible with the opposite; i.e., population heterozygote advantage could arise in a population in which every heterozygote had a worse disease outcome than either of the corresponding homozygotes ("allele-specific underdominance").
We hypothesized that DEK could bind in a sequence-specific manner to the Y-box motifs in the promoter regions of several class II MHC genes, and that gene- and allele-specific Y-box polymorphisms could affect DEK binding activity.