Example sentences for: allele-specific

How can you use “allele-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Existing data suggest that allele-specific overdominance may exist in some animal infectious diseases, but also that simple dominance and other outcomes are commonly observed [ 11 ] . Several experimental studies have examined this question using single-strain infections in animals, and while suggestions of allele-specific overdominance have been made, none of the studies has been entirely convincing.

  • The annealing/ ligation reaction therefore included both of the allele-specific OCPs (OCP-1822C and OCP-1822T, Table I), and the ERCA reaction was performed in the presence of both of the allele-specific P2 Amplifluor primers (P2-1822C-TET and P2-1822T-FAM).

  • Y-box binding activity in nuclear extracts is gene- and allele-specific

  • Second, we show that the heterogeneity of TAS positions within the CR-bounding multi-TAS regions are genetically determined: the pattern is not random but reproducible from karyonide to karyonide, and it is allele-specific, indicating that each TAS in these regions is dictated by its own cis -acting sequence, which we model below as a pause site for an exonuclease that resects the new MAC end before telomerase can act.

  • P1 is an "Amplifluor™"-primer, with a 5' hairpin and loop structure with a fluorophore and quencher at the base of the hairpin arms [ 13 12 16 ] . The two allele-specific OCPs have different backbone sequences complementary either to a FAM- or TET- labeled P1 allowing discrimination of the polymorphic base.


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