Example sentences for: allele-specific

How can you use “allele-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, allele-specific methylation patterns can be distinguished using this gene.

  • In budding yeast the active site mutation exhibits allele-specific semidominance when heterozygous with wild-type [ 51 ] , and we have made similar observations in fission yeast (W.D.

  • Second, we show that the heterogeneity of TAS positions within the CR-bounding multi-TAS regions are genetically determined: the pattern is not random but reproducible from karyonide to karyonide, and it is allele-specific, indicating that each TAS in these regions is dictated by its own cis -acting sequence, which we model below as a pause site for an exonuclease that resects the new MAC end before telomerase can act.

  • Two examples are given to illustrate the reasons for the lack of concordance between population and allele-specific effects.

  • Of the two ways described above in which MHC genotype may affect disease outcome, the first - association between a particular allele and disease outcome - has been repeatedly documented in human populations by various methods of genetic epidemiology [ 17 ] . The second kind of effect, more vigorous immune responses to a pathogen by a heterozygote as compared to homozygotes for the same alleles, which we term "allele-specific overdominance," has been suggested by several animal studies [ 18 19 20 21 ] , although none of these studies is unambiguous (see DISCUSSION).


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