Example sentences for: alignments

How can you use “alignments” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The sequence of this linker domain is moderately well conserved among organisms, with 13-19% identity and 26-34% similarity in pairwise alignments of the yeast sequence with those of human and Giardia (Table 1).

  • The overall alignment of the midasin M-domain from humans, yeast and Giardia with other MIDAS-containing proteins (three Mg-chelatases and the I-domains of three integrins) was created by first aligning the midasins, Mg-chelatases and integrins separately with the program T-Coffee [ 58 ] . The resultant three partial alignments were then combined by the profile alignment procedure of ClustalX, as above.

  • A RIO procedure based on Pfam alignments analyzes each protein domain individually since Pfam is protein family database based on individual domains [ 8 ] . In some respects, it would be preferable to analyze whole protein sequences, but well curated databases of complete protein alignments are not available (to our knowledge).

  • Gaps in the contigs were closed by a combination of DNA sequence alignments of BESs with HTGS data, clone walking using RNA probes from end clones to hybridize to the RPCI-11 gridded filters, and verification of clone positions by PCR for STSs.

  • RIO can easily be adapted to work with different sources of alignments and different alignment programs.


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