Example sentences for: alignment

How can you use “alignment” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The protein sequences of the EPK catalytic domains of the family members were aligned, and the alignment was used to construct a phenogram that illustrates the sequence relatedness between family members.

  • From the template target alignment, 3D coordinates from the FOLDLIB template are used to construct a C-alpha only PDB format file using the sequence of the target protein.

  • The amino acid sequences of the Runt domains of all each of the collected genes, together with two previously described sequences from the spider Cupiennius salei [ 15 ] , a sequence from the crayfish Pacifastacus leniusculus , and one from the nematode Meloidogyne hapla , were aligned using Clustal W [ 16 ] , as shown in Figure 2. Functionally, the Runt domain is required both for DNA binding and for interaction with its heterodimeric partner (the beta subunit), which serves to allosterically enhance the DNA binding of the Runt domain [ 1 14 ] . Superposition of the alignment and the known crystal structure of mouse Runx1 [ 14 17 ] reveals that residues that make either direct or indirect contact with DNA are invariant (marked by asterisks in Fig.

  • Partial alignment of human EPK catalytic domains

  • Such thresholds are very likely to be different for different Pfam families since families vary in the phylogenetic signal their alignment contains.


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