Example sentences for: activity-dependent

How can you use “activity-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Further advances in our understanding of signaling mechanisms that govern activity-dependent gene regulation in skeletal muscle could lead to drugs, gene therapy, or devices that can, at least in part, substitute for daily exercise.

  • Staircase, the progressive increase in developed tension (DT) during low frequency stimulation, and posttetanic potentiation, the enhancement of twitch DT following tetanic stimulation are two common forms of activity-dependent potentiation [ 1 2 3 ] . It is generally considered that the enhancement of DT during staircase and following a tetanic contraction occurs as a result of phosphorylation of the regulatory light chains of myosin [ 4 5 ] .

  • Calcineurin, a Ca 2+ /calmodulin-activated phosphatase implicated in nerve activity-dependent fiber-type specification in skeletal muscle, directly controls the phosphorylation state of the transcription factor NFAT, allowing for its translocation to the nucleus and leading to the activation of slow-type muscle proteins in cooperation with myocyte enhancer factor 2 (MEF2) proteins and other regulatory proteins (Chin et al.

  • Quite a variety of intracellular messengers have been proposed to provide the proximate signals in exercising muscles to stimulate activity-dependent gene regulation.

  • Later, during postnatal development, normal GABAergic input is required for activity-dependent plasticity in the visual cortex as shown in the Gad2 knockout mouse [ 15, 16].

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