Words similar to active-site
Example sentences for: active-site
How can you use “active-site” in a sentence? Here are some example sentences to help you improve your vocabulary:
The KilA-N, APSES and TEN-terminal domains lack the equivalent residues of the specific active-site extension of the LAGLIDADG nucleases, suggesting that the former domains do not possess nuclease activity.
It exhibits signature motifs corresponding to the regions of the active-site lysine and the interdomain interface [ 3].
Furthermore, the active-site mutant alleles of HNT2 , HNT2-His109Ala and HNT2-His109Asp , provided on plasmids pB32 and pB86, demonstrated intermediate abilities to control dinucleoside polyphosphate levels, suggesting that elevated temperature reduces the catalytic defects of these mutant enzymes.
Before this study, structure determination, biochemical studies and sequence comparisons of 2OG-Fe(II) dioxygenases [ 1, 9] had elucidated their structural fold, active-site residues and reaction mechanism.
Here, using sequence profile searches, we show that many other protein families contain the same constellation of active-site residues and are predicted to adopt the same fold.