Example sentences for: active-site

How can you use “active-site” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The KilA-N, APSES and TEN-terminal domains lack the equivalent residues of the specific active-site extension of the LAGLIDADG nucleases, suggesting that the former domains do not possess nuclease activity.

  • It exhibits signature motifs corresponding to the regions of the active-site lysine and the interdomain interface [ 3].

  • Furthermore, the active-site mutant alleles of HNT2 , HNT2-His109Ala and HNT2-His109Asp , provided on plasmids pB32 and pB86, demonstrated intermediate abilities to control dinucleoside polyphosphate levels, suggesting that elevated temperature reduces the catalytic defects of these mutant enzymes.

  • Before this study, structure determination, biochemical studies and sequence comparisons of 2OG-Fe(II) dioxygenases [ 1, 9] had elucidated their structural fold, active-site residues and reaction mechanism.

  • Here, using sequence profile searches, we show that many other protein families contain the same constellation of active-site residues and are predicted to adopt the same fold.


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