Words similar to active-site
Example sentences for: active-site
How can you use “active-site” in a sentence? Here are some example sentences to help you improve your vocabulary:
As expected, transfection of cells with DHBV DNA carrying the YMHA polymerase active-site mutant ablated all DNA synthesis (lanes 4 and 8).
Before this study, structure determination, biochemical studies and sequence comparisons of 2OG-Fe(II) dioxygenases [ 1, 9] had elucidated their structural fold, active-site residues and reaction mechanism.
This, together with the phyletic distributution of the AraC and 2OG-Fe(II) dioxygenase superfamilies, leads us to speculate that the 2OG-Fe(II) dioxygenase superfamily evolved from the AraC-like superfamily in bacteria through drastic sequence divergence that eliminated significant sequence similarity, followed by fixation of the modified active-site configuration.
Here, using sequence profile searches, we show that many other protein families contain the same constellation of active-site residues and are predicted to adopt the same fold.
It exhibits signature motifs corresponding to the regions of the active-site lysine and the interdomain interface [ 3].