Words similar to acth

Example sentences for: acth

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Adult mouse LIF over expression mediated by transfer of LIF over expressing hematopoietic cells results in a lethal, multi-systemic phenotype that includes small adrenals with a loss of the innermost cortical layer [ 28 ] . Pituitary specific LIF over expression leads to a Cushing's Syndrome-like condition of GC hyperactivity [ 29 30 ] . LIF null adult mice have normal or slightly reduced basal ACTH and GC concentrations, and are unable to respond to acute stress by increased ACTH.
Basal POMC is reduced, but inducible upon stress [ 16 ] . Thus, an obligatory function of LIF may be in the processing of POMC to ACTH during acute stress.
Some patients with critical illness have minimal or no ACTH stimulation above their baseline cortisol levels and may be unable to respond to additional physiologic stress [ 20].
We also compared average values of basal cortisol, peak cortisol and cortisol responses to ACTH between survivors and non-survivors on the first day.
GC's induce negative feedback regulation on pituitary ACTH production, as a mechanism for protecting against GC overproduction.