Example sentences for: acth

How can you use “acth” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Adult mouse LIF over expression mediated by transfer of LIF over expressing hematopoietic cells results in a lethal, multi-systemic phenotype that includes small adrenals with a loss of the innermost cortical layer [ 28 ] . Pituitary specific LIF over expression leads to a Cushing's Syndrome-like condition of GC hyperactivity [ 29 30 ] . LIF null adult mice have normal or slightly reduced basal ACTH and GC concentrations, and are unable to respond to acute stress by increased ACTH.

  • Basal POMC is reduced, but inducible upon stress [ 16 ] . Thus, an obligatory function of LIF may be in the processing of POMC to ACTH during acute stress.

  • Some patients with critical illness have minimal or no ACTH stimulation above their baseline cortisol levels and may be unable to respond to additional physiologic stress [ 20].

  • We also compared average values of basal cortisol, peak cortisol and cortisol responses to ACTH between survivors and non-survivors on the first day.

  • GC's induce negative feedback regulation on pituitary ACTH production, as a mechanism for protecting against GC overproduction.


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