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Example sentences for: achiasmatic

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Rec12 has dual roles in chiasmatic and achiasmatic (distributive) chromosome segregation during Meiosis I
The respective contributions of chiasmatic and achiasmatic (distributive) modes of chromosome segregation can be studied in organisms with naturally-occurring achiasmatic chromosomes [ 8 ] , in cells harboring non-recombined artificial chromosomes [ 9 ] , and in achiasmatic mutants [ 10 ] . Among achiasmatic mutants, those lacking the Spo11 (Rec12) protein are of particular interest because Spo11 has a key role in the initiation of recombination [ 11 ] .
In female meioses of D. melanogaster , heterochromatic pairing of homologs can substitute for chiasmata to ensure bipolar spindle attachment of bivalents and subsequent distributive segregation [ 4 5 6 8 ] . Rec12 may serve a similar role in maintaining a paired (or pseudo-paired) state between achiasmatic chromosomes prior to the first meiotic division.
Since wild-type S. pombe has 44 crossovers per meiosis (between 11 and 18 per chromosome) [ 36 ] , the mutants statistically have less than 0.1 crossovers per chromosome per meiosis and are thus achiasmatic.
The rec12-D15 (null) mutants are achiasmatic (Table 1) and, as anticipated, exhibit a high frequency of MI nondisjunction (Figures 3, 5, Table 2).