Example sentences for: abrogation

How can you use “abrogation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • LIF is also responsible for increased GFAP expression [ 69 ] , while signaling through LIFR:gp130 is critical in fostering the differentiation of neuronal precursors into astrocytes [ 70 ] mediated through STAT3 [ 71 72 73 74 ] . Glial cells respond to GC, which, in turn, can affect transcriptional control of GFAP level either positively or negatively [ 74 ] . The present study shows that GC's can play a critical role in hindering astrocyte development in the absence of LIFR as seen through the partial abrogation of this defect following exposure to RU486 in Lifr -/- mice.

  • Recent studies have shown that abrogation of BP1 expression in a leukemia cell line leads to apoptosis (Davenport GJ, Fu S, Haga SB, Do K, Stevenson H, Pinzone J, Chase MB, Berg PE, unpublished data).

  • These animals all died within 9 months from lymphomas or other extra-CNS neoplasms known to be associated with abrogation of p53 function.

  • This site was mutated into CATCGAT, which led to abrogation of the Wnt-3A response.

  • Coupled with the increased clonogenicity resulting from overexpression of BP1, these observations suggest that the expression of BP1 in breast tissue might also lead to increased survival and, conversely, that the abrogation of BP1 expression in malignant breast tissue could cause apoptosis of those cells expressing BP1.

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