Words similar to abrogated
Example sentences for: abrogated
How can you use “abrogated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Actin filament elongation would continue and RhoA dependent retraction of filamentous actin would be abrogated.
Previous reports have demonstrated that ADP-ribosylation of B-lymphoid cell lines by C3 treatment inhibits phorbol ester induced cellular homotypic aggregation [ 18 ] . Also, phorbol ester and chemoattractant (IL-8 and fMLP) induced pre-B lymphoblastoid adhesion to VCAM-1 and neutrophil adhesion to fibrinogen was abrogated in a dose-dependent manner by C3 exoenzyme [ 36 ] . This may indicate that in cells of hematopoietic lineages, the induction of an increased adhesive state may be susceptible to regulation by Rho proteins.
RNA interference (RNAi), mediated by short interfering double-stranded RNA molecules (siRNA or dsRNA), is now recognized as a major mechanism of post-transcriptional gene silencing (PTGS) in essentially all eukaryotes [ 16 ] . Recently, the technique has been successfully applied to cultured mammalian cells, whereby introduction of 21-nucleotide long synthetic dsRNA molecules corresponding to specific mRNA sequences effectively and specifically degraded the cognate mRNAs and abrogated the expression of the corresponding proteins [ 17 18 ] . This prompted us to test a similar approach to knockdown PfPP1 function in the erythrocytic P. falciparum stages.
In New1, in contrast to a deletion of the N-rich domain, deletion of the repeat did not affect aggregation of the protein or formation of the prion, but abrogated inheritance of the prion.
It has been shown that overexpression of a region of this protein encompassing the GOLD domain caused disassembly of the Golgi structure and abrogated protein transport from the ER to the Golgi [ 16].
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