Example sentences for: abrogated

How can you use “abrogated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Actin filament elongation would continue and RhoA dependent retraction of filamentous actin would be abrogated.

  • Because two studies have noted higher estrogen levels among women with A2 alleles [ 4 23 ] , it is possible that women with these genotypes have more lifetime exposure to circulating steroid hormones that is not abrogated by later age at menarche or by earlier age at first full-term pregnancy.

  • Placing cCAF in both wells abrogated cell migration, strongly suggesting that this protein chemoattracts fibroblasts (Fig 8B).

  • RNA interference (RNAi), mediated by short interfering double-stranded RNA molecules (siRNA or dsRNA), is now recognized as a major mechanism of post-transcriptional gene silencing (PTGS) in essentially all eukaryotes [ 16 ] . Recently, the technique has been successfully applied to cultured mammalian cells, whereby introduction of 21-nucleotide long synthetic dsRNA molecules corresponding to specific mRNA sequences effectively and specifically degraded the cognate mRNAs and abrogated the expression of the corresponding proteins [ 17 18 ] . This prompted us to test a similar approach to knockdown PfPP1 function in the erythrocytic P. falciparum stages.

  • Indeed, treatment of the macrophages with the proteasome inhibitor MG132, which prevents NF-κB activation [33], abrogated endotoxin-induced activation of resistin expression (data not shown).


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