Example sentences for: abrogated

How can you use “abrogated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In turn, ICER overexpression abrogated the transcriptional activity of the TH promoter, strongly suggesting ICER's involvement in Tat-mediated inhibition of gene expression [ 23 ] .

  • In New1, in contrast to a deletion of the N-rich domain, deletion of the repeat did not affect aggregation of the protein or formation of the prion, but abrogated inheritance of the prion.

  • These signaling events are generally not entirely abrogated and kinetic analyses have revealed that the sustained phases are particularly impaired in the absence of Btk [ 8, 9, 13].

  • RNA interference (RNAi), mediated by short interfering double-stranded RNA molecules (siRNA or dsRNA), is now recognized as a major mechanism of post-transcriptional gene silencing (PTGS) in essentially all eukaryotes [ 16 ] . Recently, the technique has been successfully applied to cultured mammalian cells, whereby introduction of 21-nucleotide long synthetic dsRNA molecules corresponding to specific mRNA sequences effectively and specifically degraded the cognate mRNAs and abrogated the expression of the corresponding proteins [ 17 18 ] . This prompted us to test a similar approach to knockdown PfPP1 function in the erythrocytic P. falciparum stages.

  • Actin filament elongation would continue and RhoA dependent retraction of filamentous actin would be abrogated.


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