Words similar to abrogate
Example sentences for: abrogate
How can you use “abrogate” in a sentence? Here are some example sentences to help you improve your vocabulary:
The specificity of dsRNA activity was further tested by using a dsRNA against cellular lamin A/C that was earlier shown to specifically abrogate lamin A/C synthesis in a variety of cultured cell lines [ 2 ] . As shown in Fig.
This agrees with in vitro work [ 26] that showed that blockade of TGF-β signaling did not abrogate the growth inhibitory effect of tamoxifen on breast cancer cells.
The anti-F dsRNA also had no effect on P protein levels, suggesting that such dsRNAs do not activate a general antiviral response that might abrogate all viral mRNA translation.
This was indicated by the observation that allelic [ 6] mutations of a single gene ( Lps ) in mice could entirely abrogate the response to LPS, and did so with great specificity.
Properly designed synthetic 21-nucleotide long double-stranded RNA (dsRNA) molecules can effectively and specifically abrogate translation of target RNAs without activating a general interferon response.