Example sentences for: abrogate

How can you use “abrogate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • in vitro work showing that blockade of TGF-β signalling did not abrogate the growth inhibitory effect of tamoxifen on breast cancer cells [ 26].

  • Consistent with this, the T790M mutation has been shown not to abrogate the catalytic activity of wild-type EGFR [22].

  • Specifically, we investigated whether two inhibitors, staurosporine and GF 109203X, could abrogate PMA-potentiated response of LS1034 cells to IFNg.

  • This agrees with in vitro work [ 26] that showed that blockade of TGF-β signaling did not abrogate the growth inhibitory effect of tamoxifen on breast cancer cells.

  • We have recently reported the role of the inhibitor of NF-κB (IκB) family member Bcl-3 in IL-1-induced MMP-1 expression [ 24 ] . Here we show that overexpression of Bcl-3 can partly abrogate CDDO's inhibitory effects on MMP-1 in SW-1353 cells, suggesting that Bcl-3 might be a target for CDDO.


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