Example sentences for: abrogate

How can you use “abrogate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This agrees with in vitro work [ 26] that showed that blockade of TGF-β signaling did not abrogate the growth inhibitory effect of tamoxifen on breast cancer cells.

  • Consistent with this, the T790M mutation has been shown not to abrogate the catalytic activity of wild-type EGFR [22].

  • We have recently reported the role of the inhibitor of NF-κB (IκB) family member Bcl-3 in IL-1-induced MMP-1 expression [ 24 ] . Here we show that overexpression of Bcl-3 can partly abrogate CDDO's inhibitory effects on MMP-1 in SW-1353 cells, suggesting that Bcl-3 might be a target for CDDO.

  • Properly designed synthetic 21-nucleotide long double-stranded RNA (dsRNA) molecules can effectively and specifically abrogate translation of target RNAs without activating a general interferon response.

  • Scalia, notes the Times , went on to claim that the decision does not abrogate all "genuine but innocuous differences in the ways men and women routinely interact with members of the same sex and of the opposite sex," and all the papers give his example: a football coach slapping a player's rear on the way to the field would be lawful, while the same gesture directed at the coach's (female or male) secretary might not be.


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