Example sentences for: zn-ribbon

How can you use “zn-ribbon” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It also has high affinity for binding to single-stranded DNA on its own when separated from the three tetracysteine motifs [ 36 ] . Based on the structural and DNA-binding properties of the E. coli topoisomerase I 14 kDa domain, one can conclude that it is possible for a subdomain in topoisomerase I to lose the Zn(II) binding cysteines during evolution and still maintains the Zn-ribbon structure and single-strand DNA binding properties [ 7 ] .

  • Consistent with this, the Zn-ribbon had been subsequently reused in several basal archaeo-eukaryotic transcription factors, such as TFIIB, TFIIE and TFIIS [ 67 68 71 72 73 ] .

  • Although the sequences of the Zn-ribbons of bacterial and archaeo-eukaryotic DDRP subunits have diverged considerably, their similar location in the orthologous polypeptides from different kingdoms suggests that β' subunit of LUCA already contained a Zn-ribbon.

  • Based on the crystal structure, it has been proposed that the region containing the Zn ribbon may interact with the promoter during transcription initiation in bacteria [ 23 ] . Hence, it is plausible that a nucleic-acid-binding Zn-ribbon had been recruited to the ancestral polymerase core, which consisted of the DPBB domains, and contributed to non-specific interactions with the template.

  • Additionally, the Zn-ribbon underwent duplication and elaboration in the β' subunit and was also recruited in various transcription factors.


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