Words similar to zn
Example sentences for: zn
How can you use “zn” in a sentence? Here are some example sentences to help you improve your vocabulary:
The Zn 1 site has 3 histidine residues and 1 bridging hydroxide as ligands, and the Zn 2 site has 2 histidines, 1 aspartic acid, 1 terminally-bound water, and the bridging hydroxide as ligands.
There is also another possible explanation for the varied number of tetracysteine motifs and requirement of Zn(II) for relaxation activity found in different type IA topoisomerases.
The inclusion of 100 μM ZnCl 2 in the assay buffer resulted in slightly lower values of K m and higher values for k cat [ 36 ] . The inclusion of higher concentrations of Zn(II) did not further affect the steady-state kinetic constants.
The hyperthermophilic topoisomerase I from Thermotoga maritima has been shown to coordinate one Zn(II) with a unique tetracysteine motif Cys-X-Cys-X 16 -Cys-X-Cys but Zn(II) binding is not required for relaxation activity [ 33 ] . The sequence of this unique tetracysteine motifs is somewhat different from those present in other type IA topoisomerases in that the other tetracysteine motifs always had at least two amino acids separating the pairs of cysteines (Cys-X 2-11 -Cys), instead of just one amino acid (Cys-X-Cys) in T. maritima topoisomerase I [ 33 ] . Therefore the structure and function of the single Zn(II) binding motif in T. maritima may differ from the multiple Zn(II) binding motifs in E. coli topoisomerase I. Direct interaction between DNA and the T. maritima Zn(II) binding motif has not been demonstrated.
The 14 kDa C-terminal region of E. coli topoisomerase I has been classified based on its structure to be in the Zn-ribbon superfamily [SCOP release 1.50, 7] even though it does not bind Zn(II).
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