Words similar to zap-
Example sentences for: zap-
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Some of the earliest changes that occur following BCR engagement are the activation of several non-receptor protein tyrosine kinases (PTKs), including p55 blk (Blk), p59 fyn (Fyn) and p53/56 lyn (Lyn) of the Src family [ 31 ] , Btk of the Itk/Tec family [ 32 33 ] and p72 Syk (Syk) of the Syk/ZAP-70 family [ 34 ] . The importance of Syk in BCR signaling and lymphocyte development has been clearly demonstrated using gene inactivation approaches.
In contrast, these pathways are completely inhibited in the absence of the Syk/ZAP-70 family tyrosine kinase Syk [ 14].
Engagement of antigen receptors on lymphocytes leads to the rapid sequential activation of non-receptor tyrosine kinases, including well-studied members of the Src and the ZAP-70/Syk families [ 1, 2].