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Example sentences for: yrh

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Additionally, a search of the NR database with a position-specific scoring matrix (PSSM) that included all unique RDRP and YRH sequences detected, with borderline E-values, a large protein from Corynebacterium glutamicum (Cgl1702), which also contained a DXDGD motif.
Eukaryotes might have acquired the YRH gene from a bacteriophage at an early stage of their evolution and retained the RDRPs thanks to the selective advantage conferred by the new level of gene expression regulation mediated, in part, by these enzymes.
The eukaryotic RDRP is part of a large ensemble of functionally linked proteins, which include the Dicer helicase-nuclease, PIWI family proteins, the Hen-2/Corymbosa-like RNA methylase, AlkB-related RNA demethylases, and Lin28-like RNA-binding proteins [ 1 45 46 ] . Since no closely related homologs of any of these proteins are encoded in the genomes of the phages that encode YRH proteins, the latter are unlikely to function in a biological context similar to that of the eukaryotic RDRPs.
Should that be the case, the YRH proteins could be late surviving derivatives of these ancient enzymes, which apparently have been shunned from cellular life forms during the evolution of prokaryotes.
All RDRP sequences contain two closely spaced lysines, which are conserved in the YRH proteins (Fig.