Words similar to yqxp
Example sentences for: yqxp
How can you use “yqxp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Using different regions of the Cas SD containing either the YDXP or the YQXP motifs, we could demonstrate that v-crk specifically interacts with the C-terminal YDXP motifs when tyrosine phosphorylated.
By contrast, co-expression of these fusions along with v-crk results in stable tyrosine phosphorylation of the 3' C-terminal YDXP motifs and the full length Cas SD (carrying both motifs), but not the 5' N-terminal YQXP motifs (Fig.
The v-crk SH2 domain interacts with YXXP motifs upon phosphorylation, suggesting that both of these regions may be able to interact with v-crk [ 37 ] . Fusions of the kinase inactive Src kinase domain and either the full Cas SD, the 5' region of the Cas SD (Cas(5'SD), containing 4 YQXP motifs) or the 3' of the Cas SD (Cas(3'SD), containing 9 YDXP motifs), are not stably tyrosine phosphorylated when expressed alone in cells (data not shown and see Fig.
These data indicate that the v-crk SH2 domain interacts with the C-terminal YDXP motifs, and as suggested by Birge et al, v-crk may be able to protect them from dephosphorylation and/or induces their phosphorylation [ 12 ] . They also suggest that the YQXP motifs may be involved in binding to other intracellular signaling molecules.
Since crk is the major protein reported to bind to the Cas SD, our data suggest that the YQXP motifs may interact with other yet to be identified downstream effectors.