Example sentences for: xvq
How can you use “xvq” in a sentence? Here are some example sentences to help you improve your vocabulary:
This interval includes approximately 600 kb of sequence spanning FISH probes RP11-932O9, RP11-605N15, RP11-422F16, RP11-40J8 and RP11-382B18, all of which produced dual FISH signals flanking the centromere in PTR XVq and XVp (Figures 3, 4).
We next investigated the nature of the sequence underlying the pericentric inversion breakpoint by extracting the 1 Mb interval encompassing the sequence between the most distal PTR XVp probe, RP11-360J18, and the most proximal PTR XVq probe, RP11-736I24, from the November 2002 human genome assembly.
Interestingly, the extent of the segmental duplications in the 1 Mb region examined was restricted to the clones that showed the dual FISH signal in PTR XVp and XVq and each clone that produced dual FISH signals contained a GLP/LCR15 duplicon by sequence analysis (Figure 4).
We selected probes to refine the chimpanzee XVq11-q13 pericentric inversion breakpoint on the basis of YAC maps of human 15q11-q13, in addition to the genome assemblies produced by the Human Genome Project [ 30 31 ] . We chose BACs targeted for complete sequencing (Figure 1) so that the underlying sequence of each probe would be available for further analysis pending comparative FISH results.
In addition, FISH results with probe RP11-30N16, which contains the intact donor CHRNA7 locus, did not produce dual FISH signals on PTR XVp and XVq, further demonstrating this sequence is not involved in the evolutionary rearrangement.
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