Example sentences for: xvp
How can you use “xvp” in a sentence? Here are some example sentences to help you improve your vocabulary:
We next investigated the nature of the sequence underlying the pericentric inversion breakpoint by extracting the 1 Mb interval encompassing the sequence between the most distal PTR XVp probe, RP11-360J18, and the most proximal PTR XVq probe, RP11-736I24, from the November 2002 human genome assembly.
Our FISH results using probe RP11-40J8, which demonstrated dual signals on PTR XVp and XVq, indicated we had reached the site of the pericentric inversion, or alternatively a sequence within RP11-40J8 had been duplicated to both arms of PTR XV.
It has been shown in multiple studies that regions of segmental duplication can be associated with evolutionary rearrangements [ 8 29 ] . The pericentric inversion of chimpanzee XVp, having been localized to a site of multiple segmental duplications in the human genome, indicates that the evolutionary rearrangement is likely to involve such sequences.
From on its position in the human assembly, clone RP11-360J18 was the most distal to show a FISH signal on a single PTR chromosome arm (XVp).
In addition, FISH results with probe RP11-30N16, which contains the intact donor CHRNA7 locus, did not produce dual FISH signals on PTR XVp and XVq, further demonstrating this sequence is not involved in the evolutionary rearrangement.