Example sentences for: whr
How can you use “whr” in a sentence? Here are some example sentences to help you improve your vocabulary:
The WHR has emerged as an important metameter of the association between central adiposity and many obesity-related diseases.
Overall, categories of WHR were not significantly associated with the risk of breast cancer but there was a marginally significant test of trend for a positive association between increasing WHR and breast cancer risk.
Studies of WHR and the risk of breast cancer are limited by systematic bias in the measurement of WHR across studies [ 36 ] , which may have been controlled somewhat in this study by using nurse interviewers and adhering to the World Health Organization MONICA guidelines [ 10 ] . In case-control studies like the present one, selection and recall bias can be problematic.
The WHR, a measure of central adiposity, is gaining increased use as a measure of etiologically significant obesity and is thought to be more closely related to pathology, especially coronary heart disease, diabetes mellitus and stroke [ 7 ] . The metabolic changes that accompany obesity include peripheral hyperinsulinemia, hyperglycemia and glucose intolerance, hypertriglyceridemia, decreased serum low-density lipoprotein, increased serum very low-density lipoprotein, increased serum leptin, dyslipidemia, increased serum cortisol clearance, increased serum C-peptide level, downregulation of insulin receptors and an exaggerated insulin response to an oral glucose load [ 12 13 14 15 ] . These changes, especially when they occur in early adulthood, may be of fundamental importance in the development of breast cancer [ 9 16 ] .
In the Nurses' Health Study, the adjusted risk for the highest quintile compared with the lowest quintile of WHR among postmenopausal women who had never used hormone replacement therapy was 1.85 (95% confidence interval = 1.25-2.
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