Example sentences for: whr
How can you use “whr” in a sentence? Here are some example sentences to help you improve your vocabulary:
The WHR, a measure of central adiposity, is gaining increased use as a measure of etiologically significant obesity and is thought to be more closely related to pathology, especially coronary heart disease, diabetes mellitus and stroke [ 7 ] . The metabolic changes that accompany obesity include peripheral hyperinsulinemia, hyperglycemia and glucose intolerance, hypertriglyceridemia, decreased serum low-density lipoprotein, increased serum very low-density lipoprotein, increased serum leptin, dyslipidemia, increased serum cortisol clearance, increased serum C-peptide level, downregulation of insulin receptors and an exaggerated insulin response to an oral glucose load [ 12 13 14 15 ] . These changes, especially when they occur in early adulthood, may be of fundamental importance in the development of breast cancer [ 9 16 ] .
In contrast, the Iowa Women's Health Study showed no association with WHR, and an earlier report of interaction with family history appeared to have attenuated with time [ 25 26 ] . In the New York University Women's Health Study, the multivariable analysis showed an association between the lowest quintile and the highest quintile of WHR and breast cancer of 1.72 (95% confidence interval = 1.0-3.
The body mass index (BMI) (weight [kg]/height [m 2]; obesity = BMI ≥ 30) and WHR were computed (waist circumference [cm]/hip circumference [cm]), and four subjects with WHR > 1.2 and WHR < 0.6 were excluded.
Studies of WHR and the risk of breast cancer are limited by systematic bias in the measurement of WHR across studies [ 36 ] , which may have been controlled somewhat in this study by using nurse interviewers and adhering to the World Health Organization MONICA guidelines [ 10 ] . In case-control studies like the present one, selection and recall bias can be problematic.
The WHR has emerged as an important metameter of the association between central adiposity and many obesity-related diseases.
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