Words similar to voltage-gated
Example sentences for: voltage-gated
How can you use “voltage-gated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Because the target of DDT and pyrethroid insecticides is the voltage-gated Na +channel [ 15 ] , and considering that the anti-malarial quinine blocks K +channels, insights into the ion channels in the genomes of this mosquito and other insects may be useful for investigating how DDT and other pesticides may be used with greatest efficacy and safety.
This is in part because these channels regulate the cytoplasmic concentrations of K +, Ca 2+, and Na +ions [ 1 2 3 4 5 6 7 8 9 10 ] . The diversity of voltage-gated K +channels and currents present in these "non-excitable" (non-muscle, non-nerve) cells is impressive.
Earlier studies in the voltage-gated Na +channel had shown that pore function was not compromised when the II-III linker or III-IV linker was cut and the two fragments were coexpressed each in a separate vector [ 37 ] . We would thus conclude that in the case of the Ca 2+channel, an intact II-III loop is essential for this function since neither fs-α 1S nor the combined expression of the two truncated fragments (not shown) was able to rescue Ca 2+current.
I have identified eight voltage-gated K +channels, three Eag-family, three Slo-family and six inward rectifier channel genes using this search.
Analysis of the crystal structure of GlpF suggests that potential ion binding sites may be located in the central pore, at the four-fold axis of symmetry in the tetrameric association of subunits that form the channel [ 15 ] . Interestingly, this arrangement of a tetramer of subunits to form a central ion pore is a hallmark of the family of voltage-gated ion channels [ 23 ] , which rely on a tetrameric organization to create a central pore for ions that is lined by sequences contributed from all four subunits.
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