Words similar to voltage-gated
Example sentences for: voltage-gated
How can you use “voltage-gated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Because the target of DDT and pyrethroid insecticides is the voltage-gated Na +channel [ 15 ] , and considering that the anti-malarial quinine blocks K +channels, insights into the ion channels in the genomes of this mosquito and other insects may be useful for investigating how DDT and other pesticides may be used with greatest efficacy and safety.
Tetraethylammonium is known as a pore-occluding blocker of voltage-gated potassium channels [ 1 ] , but it also blocks other cationic channels such as calcium-dependent K +channels [ 2 3 ] and the nicotinic acetylcholine receptor [ 4 ] . TEA at 0.1 to 10 mM also inhibits osmotic water flux through human AQP1 channels expressed in Xenopus oocytes, decreasing the net swelling rate in hypotonic saline by 30-40% as compared to AQP1-expressing oocytes not treated with TEA [ 5 ] . This blocking effect on osmotic water flux was demonstrated to involve AQP1 channels specifically by using site-directed mutagenesis (tyrosine 186 to phenylalanine) to generate a Y186F AQP1 channel that is insensitive to block by TEA, but retains sensitivity to block by mercury.
Drug block of the voltage-gated potassium channels that conduct the ultra-rapid delayed rectifier current I Kur is associated with increased intracellular potassium concentration, increased cell volume, activation of chloride influx and hyperpolarization of resting membrane potential.
A number of ion channels were found to be expressed higher in the dorsal spinal cord, including, voltage-gated sodium channel type VI (SCAN6A), a putative four repeat ion channel, NMDA receptor NR1, and potassium channel Kv3.
Of the four voltage-gated K +-channel types Kv1-4, the Shaker , or Kv1 channel gene is, from a genomic perspective, arguably the most complex.
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