Words similar to virucidal
Example sentences for: virucidal
How can you use “virucidal” in a sentence? Here are some example sentences to help you improve your vocabulary:
Smallpox, while not found in the world's population at present, remains a potential health hazard especially due to the possibility of its use as a bioweapon [ 1 2 3 4 5 ] . There is currently no accepted treatment for smallpox, although a number of agents have been evaluated [ 6 ] . Therefore, new therapeutic or virucidal agents could have great utility in slowing both the progression and spread of the disease in an epidemic situation.
Among the two carboxylate polymers (Carbomer 974P and CAP), only soluble CAP (at neutral pH) was able to elicit the formation of gp41 six-helix bundles in both HIV-1 IIIB and BaL and was virucidal against both of these viruses.
To avoid this, CAP in micronized form (which does not aggregate at low pH), instead of CAP in soluble form is being considered as a topical microbicide [ 30 31 32 33 34 35 ] . Micronized CAP (Aquateric) was shown to be virucidal against HIV-1, herpesviruses and several nonviral sexually transmitted disease (STD) pathogens [ 30 31 32 33 34 ] . The virucidal activity of micronized CAP could at least partly be explained by its buffering capacity at low pH [ 40 ] since it is a free acid while other anionic polymeric microbicide candidates (except BufferGel, the active ingredient of which is Carbomer 974P [ 27 ] ) are sodium salts.
This was confirmed by the results of assays for virucidal activity.
Such studies were expected to elucidate further the mechanisms involved in the antiviral/virucidal activity of CAP and to contribute to the potential development of microbicides combining two or more anti-HIV-1 compounds with distinct target sites.
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