Words similar to vesiculation

Example sentences for: vesiculation

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The process of membrane vesiculation and MP-release in platelets has been shown to require a calpain-dependent dissociation of membrane proteins from the submembrane cytoskeleton and most likely involves intracellular signaling by platelet protein kinases [ 10 ] . Besides platelets stimulated by various agonists such as thrombin with collagen or the complement complex C5b-9 [ 7 11 ] , a release of PS-containing membrane MP was demonstrated in other cell types such as endotoxin-stimulated monocytes [ 12 ] , polymorphonuclear leucocytes stimulated with the chemotactic peptide FMLP [ 13 ] or apoptotic T-lymphocytes [ 14 ] . The normal restriction of PS to the inner surface of the plasma membrane becomes perturbed in apoptotic cells [ 15 16 ] . When exposed, PS is a determinant for phagocyte recognition of cells to be cleared.
Cell membrane vesiculation and release of MP is considered to belong to the execution stage of apoptosis where the fate of the cell is sealed.
For instance, in neurons undergoing apoptosis, morphologic changes were characterized by a highly ordered sequence of organelle abnormalities, with swelling of endoplasmic reticulum and Golgi vesiculation that preceded most nuclear changes or mitochondrial disruption [ 27 28 ] .