Words similar to v-crk

Example sentences for: v-crk

How can you use “v-crk” in a sentence? Here are some example sentences to help you improve your vocabulary:

In particular, we found that the tyrosine phosphorylated Cas SD domain blocked v-crk mediated activation of the JNK pathway.
Thus while both sets of motifs in the Cas SD have been thought to interact with the v-crk SH2 domain, we demonstrated that this domain only interacts with the YDXP motifs.
These data suggest that the kinase inactive fusion with the Cas SD is either transiently tyrosine phosphorylated in cells and v-crk protects them from being dephosphorylated by interacting with them via its SH2 domain, or alternatively, that v-crk induces their tyrosine phosphorylation.
Investigators have shown that v-crk interacts via its SH2 domain with the substrate domain of Cas [ 6 ] . Association of v-crk with endogenous Cas is believed to protect the phosphorylation status of this molecule due to protection from phosphatases [ 12 ] . Expression of an unphosphorylated Cas SD along with v-crk should therefore result in stable tyrosine phosphorylation of the Cas SD if they interact.
By contrast, co-expression of these fusions along with v-crk results in stable tyrosine phosphorylation of the 3' C-terminal YDXP motifs and the full length Cas SD (carrying both motifs), but not the 5' N-terminal YQXP motifs (Fig.