Words similar to v-crk
Example sentences for: v-crk
How can you use “v-crk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus while both sets of motifs in the Cas SD have been thought to interact with the v-crk SH2 domain, we demonstrated that this domain only interacts with the YDXP motifs.
Moreover, in the absence of stable tyrosine phosphorylation as seen in the Src kinase inactive fusions, v-crk could either induce their phosphorylation, or protect transiently phosphorylated YDXP motifs from dephosphorylation through yet unknown mechanisms.
Tyrosine phosphorylated Cas SD acts as a decoy for v-crk and endogenous c-crk
In addition, we found that expression of the tyrosine phosphorylated Cas SD domain in v-crk transformed cells reduced their ability to grow in soft agar, a measure of their transformation.
These data indicate that the v-crk SH2 domain interacts with the C-terminal YDXP motifs, and as suggested by Birge et al, v-crk may be able to protect them from dephosphorylation and/or induces their phosphorylation [ 12 ] . They also suggest that the YQXP motifs may be involved in binding to other intracellular signaling molecules.