Words similar to v-crk

Example sentences for: v-crk

How can you use “v-crk” in a sentence? Here are some example sentences to help you improve your vocabulary:

The JNK pathway is regulated by interaction of c- or v-crk with Cas via the substrate domain [ 38 ] . In determining which pathways are affected in our stable cell lines generated, we determined if JNK was activated in the v-crk transformed cells, and if the tyrosine phosphorylated Cas chimera was affecting this activation.
We also verified that the tyrosine phosphorylated Cas chimera could affect the ability of v-crk to activate the JNK pathway in transient transfection experiments (Fig.
In particular, we found that the tyrosine phosphorylated Cas SD domain blocked v-crk mediated activation of the JNK pathway.
Initially, we expressed the Src KM/Cas(SD) (entire Cas SD) in Cos-7 cells alone, or along with wild type (WT) v-crk, or v-crk SH2 or SH3 mutants and assayed for tyrosine phosphorylation and association by co-immunoprecipitation (Fig.
Moreover, in the absence of stable tyrosine phosphorylation as seen in the Src kinase inactive fusions, v-crk could either induce their phosphorylation, or protect transiently phosphorylated YDXP motifs from dephosphorylation through yet unknown mechanisms.