Example sentences for: v-

How can you use “v-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • He touted the television V-chip; praised the Kennedy-Kassebaum law (an ultra-therapeutic law that guarantees portability of insurance but places no ceiling on the rates insurers can charge); applauded the ban on "assault" rifles; and bragged about the new FDA regulations that curb the advertising and sale of cigarettes to children.

  • The cell surface expressed integrins can control this process by physically interacting with the extracellular matrix proteins and other cell surface proteins on endothelial cells lining the blood vessel wall [ 1 ] . These integrins signal adhesion and migration by communicating with several tyrosine kinases inside the cell, including the Focal Adhesion Kinase (FAK) and Src family kinases [ 1 2 ] . Src kinases control the activation of FAK, as well as the tyrosine phosphorylation of critical substrates that regulate adhesion and migration [ 3 ] . Indeed, colon cancer cells with high metastatic potential have elevated levels of Src activity or activating mutations in the Src gene [ 4 5 ] . One Src substrate that is involved in regulating an important signaling node in this process is the adaptor protein p130 cas (Cas) [ 6 7 8 9 10 ] . Cas appears to play a central role in the transformation process by several oncogenes including ras, ornithine decarboxylase (ODC), v-Src, v-crk, and Bcr-Abl, as these tumors all have elevated levels of tyrosine phosphorylated Cas [ 6 11 12 13 ] . Cells from mice that lack Cas have much reduced migration and are resistant to transformation by v-Src, while expression of Cas anti-sense RNA in cells transformed with ras, v-Src or ODC result in reversion of the transformed phenotype [ 11 14 15 ] . Furthermore, increased expression of Cas can rescue cell migration and adhesion in cells expressing the tumor suppressor PTEN, and can enhance cell migration and adhesion in normal cells, with a major role being played by the substrate domain [ 16 17 ] .

  • Numbers of annexin V-positive cells were reduced 40% by the addition of anti-TRAIL antibody (2 μg/ml) to S. aureus -infected osteoblast cultures.

  • Interestingly, three genes whose products are known to promote viral replication were associated with v- myb and v- abl oncogenes (shared terms: 'virus', 'transformation' or 'leukemia'): TAX1BP1 (Tax1-binding protein 1), CREB3 (cAMP-response element binding protein 3/LZIP) and TARBP2 (TAR-binding protein 2) (Figure 7a) [ 20, 21, 22].

  • Thus, it is possible that local expression of v-IL-10 or IL-1 and TNF inhibitors modulates the activity of dendritic cells.


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