Example sentences for: v-

How can you use “v-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The cell surface expressed integrins can control this process by physically interacting with the extracellular matrix proteins and other cell surface proteins on endothelial cells lining the blood vessel wall [ 1 ] . These integrins signal adhesion and migration by communicating with several tyrosine kinases inside the cell, including the Focal Adhesion Kinase (FAK) and Src family kinases [ 1 2 ] . Src kinases control the activation of FAK, as well as the tyrosine phosphorylation of critical substrates that regulate adhesion and migration [ 3 ] . Indeed, colon cancer cells with high metastatic potential have elevated levels of Src activity or activating mutations in the Src gene [ 4 5 ] . One Src substrate that is involved in regulating an important signaling node in this process is the adaptor protein p130 cas (Cas) [ 6 7 8 9 10 ] . Cas appears to play a central role in the transformation process by several oncogenes including ras, ornithine decarboxylase (ODC), v-Src, v-crk, and Bcr-Abl, as these tumors all have elevated levels of tyrosine phosphorylated Cas [ 6 11 12 13 ] . Cells from mice that lack Cas have much reduced migration and are resistant to transformation by v-Src, while expression of Cas anti-sense RNA in cells transformed with ras, v-Src or ODC result in reversion of the transformed phenotype [ 11 14 15 ] . Furthermore, increased expression of Cas can rescue cell migration and adhesion in cells expressing the tumor suppressor PTEN, and can enhance cell migration and adhesion in normal cells, with a major role being played by the substrate domain [ 16 17 ] .

  • 3) thus supporting the hypothesis that annexin V-binding MP-release takes place in the initial phase of apoptosis.

  • This fact is reflected in the analysis of literature profiles, as groups of genes could be found to be associated with brain tissues (Figure 7f, for example, HPCA (hippocalcin), SYP (synaptophysin), GRIK1 (glutamate receptor, ionotropic, kainate 1), APLP (amyloid beta A4 precursor-like protein)), immune cells (Figure 7b, for example, CD40, IL15RA (IL-15 receptor, alpha chain), LILB4 (leukocyte immunoglobulin-like receptor 4)) or tumor cells (Figure 7a, for example, MYBL1 (v- myb avian myeloblastosis viral oncogene), ABL2 (v- abl Abelson murine leukemia viral oncogene homolog 2)).

  • The presence of CD59 on all annexin V-binding MP corresponds to the high expression of this glycosylphosphatidylinositol anchored glycoprotein on endothelial cells.

  • Because of the high degree of sequence similarity the archaeal ATP synthase (A-type ATPase) is sometimes labeled as vacuolar or V-type ATPase.


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