Example sentences for: urokinase

How can you use “urokinase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • After 2 h of incubation at 37 °C, 50 μl detection reagent containing a modified urokinase and S-2444 peptide substrate was added to all wells.

  • PN-1 has four known target proteases: urokinase plasminogen activator (uPA), tissue type plasminogen activator (tPA), thrombin and trypsin [ 17 ] . Evidence exists for a role of both trypsin [ 18 19 ] and uPA [ 20 21 ] in migratory processes.

  • The overall effect of urokinase in the antigen-induced arthritis model seems to be beneficial, because chronic joint inflammation and bone erosion are significantly worse in urokinase-deficient mice [ 30 ] . However, the ability of urokinase-generated mactinin to enhance proteolysis might be deleterious.

  • The ATF plasmid was constructed by deleting the DNA sequences encoding amino acids 139 to 401 of the urokinase cDNA plasmid.

  • Plasminogen activator inhibitor-1 (PAI-1) is a serine proteinase inhibitor in the serpin superfamily [ 1 2 3 ] . This 50 kDa glycoprotein is apparently the most important physiological inhibitor of tissue-type plasminogen activator (tPA) and of urokinase plasminogen activator (uPA).


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