Words similar to urokinase
Example sentences for: urokinase
How can you use “urokinase” in a sentence? Here are some example sentences to help you improve your vocabulary:
Plasminogen activator inhibitor-1 (PAI-1) is a serine proteinase inhibitor in the serpin superfamily [ 1 2 3 ] . This 50 kDa glycoprotein is apparently the most important physiological inhibitor of tissue-type plasminogen activator (tPA) and of urokinase plasminogen activator (uPA).
An mhATF-BPTI enzyme-linked immunoabsorbent assay (ELISA) was developed by Dr. P. Quax (Toegepast Natuurwetenschappelijk Onderzoek institute), using a monoclonal antibody specific for the ATF as the capture antibody and a polyclonal antibody directed against BPTI as the detector antibody [ 18 ] . As a standard we used medium of Ad5 Adapt mhAB infected CHO cell culture in which the mhATF-BPTI concentration was determined by an urokinase ELISA.
We have shown that α-actinin is abundant in the bone marrow stroma matrix, presumably at focal adhesion sites [ 5 ] . We have also reported that a 31 kDa amino-terminal α-actinin fragment, which we have named mactinin, is generated by the degradation of extracellular α-actinin by monocyte-secreted urokinase [ 6 ] . Furthermore, we have demonstrated that mactinin is present in inflammation caused by Pneumocystis carinii pneumonia, by examining bronchoalveolar lavage fluid from mice with infection [ 6 ] . It was not present in mice not challenged with P. carinii , suggesting that inflammaton is necessary for mactinin formation.
uPAR: Urokinase Receptor
This example illustrates how functional relationships that could not be deduced from gene names were uncovered through the analysis of patterns of term occurrence: matrix metalloproteinases (MMP1, 10, 14) and urokinase plasminogen activator (UPA, SPARC) are matrix-interacting molecules involved in tumor invasion and metastasis.
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