Words similar to urokinase-generated

Example sentences for: urokinase-generated

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The plasminogen activators, tissue type and urokinase type, have been reported to be both deleterious in inflammation, owing to the proteolysis of tissue proteins, and beneficial because of fibrinolytic activity [ 26 ] . The presence of both increased urokinase and plasmin inhibitors in rheumatoid arthritis synovial tissue suggests a complex role for urokinase in this disease [ 27 28 29 ] that seems pertinent to our finding of urokinase-generated mactinin in the arthritis fluid samples.
The overall effect of urokinase in the antigen-induced arthritis model seems to be beneficial, because chronic joint inflammation and bone erosion are significantly worse in urokinase-deficient mice [ 30 ] . However, the ability of urokinase-generated mactinin to enhance proteolysis might be deleterious.