Words similar to urogenital
Example sentences for: urogenital
How can you use “urogenital” in a sentence? Here are some example sentences to help you improve your vocabulary:
Development of the male genitalia is largely controlled by cells in the urogenital mesenchyme that express androgen receptors (AR) [ 1 2 ] . Germline mutations of the AR gene produce a spectrum of developmental abnormalities in 46,XY individuals ranging from infertility or mild hypospadias to complete feminization, which are collectively referred to as the androgen insensitivity syndrome (AIS).
As cultured genital fibroblasts originate from the urogenital mesenchyme and retain expression of the AR in vitro , we compared gene-expression patterns in cultured genital fibroblasts from normal 46,XY males and from 46,XY females with severe or complete AIS, using DNA microarrays representing 32,968 distinct human genes.
Comparison of the expression patterns of genital fibroblasts from 46,XY normal males and 46,XY females with inactivated AR provides a window on the AR-dependent gene-expression programs within the urogenital mesenchyme, which contribute to the development and structural integrity of male and female genitalia.
The primary support for the pelvic organs comes from the pelvic floor muscles [ 1 2 ] . This suggests that an alteration to the levator ani supportive function may significantly contribute to the pathogenesis of PFD [ 3 ] , which affect 5% of younger and nearly 50% of elderly women [ 2 ] . In women, the levator muscles form a horizontal shelf with an anterior midline cleft (the urogenital hiatus) through which the urethra, vagina, and rectum pass.
Confirming the subtractive manner in which ASW was cloned, both groups found that ASW mRNA is highly expressed in the female urogenital ridge at the stages preceding and during sexual differentiation [ 33, 34].
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