Example sentences for: tyrosines

How can you use “tyrosines” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The mutation of one of the tyrosines (Y318F) in the δ-OR or the presence of the Src inhibitor, PP1, significantly reduces tyrosine phosphorylation of this receptor and its ability to activate ERKs [ 11 13 ] . However, a small degree of δ-OR agonist-mediated ERK activation remained in cells expressing the Y318F mutant receptor, suggesting that a second mechanism or an additional tyrosine could be involved.

  • PR was obtained in 85% purity, assuming that values of ε 280 and ε 546 for pR are the same as for bR solubilized in DMPC/cholate/SDS mixtures at pH 8 (ε 280 = 7.85 × 10 4cm -1M -1and ε 551 = 4.8 × 10 4cm -1M -1) [ 5 ] . This assumption is actually expected to underestimate the purity of pR produced, by up to ~20%, since the pR we expressed has 10 tryptophan and 14 tyrosine residues, as compared to 8 tryptophans and 11 tyrosines in bR from H. salinarum.

  • We can also use this approach to ask which tyrosines within the SD of Cas can act as decoys for specific downstream signals attributed to the SD of Cas.

  • Although these distinctive features suggest that Rlk may have atypical functions, Rlk shares with Btk kinases the homologous proline-rich motif that binds the SH3 domains of Src kinases and the tyrosines at equivalent sites in the SH3 and kinase domains.

  • Understanding the function of this substrate domain and the tyrosines within it could lead to a better understanding of the signaling pathways regulated by this protein.


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