Words similar to tyrosines
Example sentences for: tyrosines
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Second, molecules with the Y130E mutations did not co-immunoprecipitate with the BCR [ 58 ] . A second example involves an in vitro model of histamine release in the Syk-deficient RBL-2H3 cell line [ 59 ] . When tyrosines 519 and 520 were mutated and introduced into Syk-deficient RBL-2H3 cells, these Syk molecules were capable of phosphorylation of c3b substrate in an ICKA.
The CCR5 peptide lacking sulfated tyrosines did not induce the six-helix bundles.
The 5-HT 3 R agonist m CPBG showed a similar profile for the changes in K i values resulting from mutations of the three tyrosines (Figure 4B).
PR was obtained in 85% purity, assuming that values of ε 280 and ε 546 for pR are the same as for bR solubilized in DMPC/cholate/SDS mixtures at pH 8 (ε 280 = 7.85 × 10 4cm -1M -1and ε 551 = 4.8 × 10 4cm -1M -1) [ 5 ] . This assumption is actually expected to underestimate the purity of pR produced, by up to ~20%, since the pR we expressed has 10 tryptophan and 14 tyrosine residues, as compared to 8 tryptophans and 11 tyrosines in bR from H. salinarum.
A number of proteins have been identified that bind to the substrate domain of Cas, however the large number of tyrosines and potential binding sites for downstream effectors suggest that there may be more.